Effect of Xifeng Dingchan Pill on the Syndrome of Liver and Kidney Deficiency of Parkinson’s Disease:A Report of 30 Cases

BAI Qinglin1; MA Yunzhi2

doi:10.13288/j.11-2166/r.2010.02.031

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Effect of Xifeng Dingchan Pill on the Syndrome of Liver and Kidney Deficiency of Parkinson’s Disease:A Report of 30 Cases

更新时间：2021-11-17

- Effect of Xifeng Dingchan Pill on the Syndrome of Liver and Kidney Deficiency of Parkinson’s Disease:A Report of 30 Cases
- Journal of Traditional Chinese Medicine Vol. 51, Issue 2, Pages: 125-127(2010)
- 作者机构：
  
  1. 河南省中医药研究院
  2. 河南中医学院第一附属医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2010.02.031
  CLC： R277.7
- Published：2010
- 稿件说明：
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[1]白清林,马云枝.熄风定颤丸治疗肝肾不足型帕金森病患者30例临床观察[J].中医杂志,2010,51(02):125-127+131.

BAI Qinglin1, MA Yunzhi2. Effect of Xifeng Dingchan Pill on the Syndrome of Liver and Kidney Deficiency of Parkinson’s Disease:A Report of 30 Cases[J]. Journal of Traditional Chinese Medicine2010, 51(2): 125-127.
[1]白清林,马云枝.熄风定颤丸治疗肝肾不足型帕金森病患者30例临床观察[J].中医杂志,2010,51(02):125-127+131. DOI： 10.13288/j.11-2166/r.2010.02.031.

BAI Qinglin1, MA Yunzhi2. Effect of Xifeng Dingchan Pill on the Syndrome of Liver and Kidney Deficiency of Parkinson’s Disease:A Report of 30 Cases[J]. Journal of Traditional Chinese Medicine2010, 51(2): 125-127. DOI： 10.13288/j.11-2166/r.2010.02.031.

摘要

目的评价熄风定颤丸对肝肾不足型帕金森病（PD）患者的治疗作用。方法将纳入的60例PD患者按标准对照1∶1的比例

随机分为治疗组、对照组各30例。两组均以美多巴为基础治疗药

治疗组加服中药熄风定颤丸。通过对不同时点Webster总评分、PD主症单因子评分的变化进行疗效的比较

评估熄风定颤丸对PD的治疗作用。结果治疗组总有效率为76.67%

对照组为53.33%

治疗组优于对照组（P<0.05）;治疗组治疗后4、8、12周Webster总评分均较治疗前明显下降

且随疗程延长

降低更加明显;治疗组对静止性震颤、强直、双手动作减少因子Webster单因子评分的改善明显优于对照组（P<0.05）。结论熄风定颤丸可有效降低PD患者Webster评分

显著改善PD患者的临床症状。

Abstract

Objective To evaluate the therapeutic effect of Xifeng Dingchan Pill （Pill for stopping wind and tremor） on Parkinson’s disease （PD）.Methods Sixty PD patients were randomized into a treatment and a control group. The treatment group （30 cases） was given madopar and Xifeng Dingchan Pill and the control group （30 cases） was administered madopar only. The effect Xifeng Dingchan Pill was evaluated according to the changes of Webster score and PD symptom factor score.Results The total effective rate of the treatment group was 76.67%

higher than 53.33% in the control group （P<0.05）. The total webster score of the treatment group in 4

12 weeks after treatment was significantly reduced than before treatment

and the effect was more remarkable with the treatment course prolonged. The improvement of Webster single factor score of resting tremor

rigidity

and hand trembling was significantly better than that of the control group （P<0.05）.Conclusion Xifeng Dingchan Pill is effective to lower the Webster score and improves the clinical symptoms of PD patients.

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