Objective To study the rule of distribution and evol vement of TCM syn dromes in HIV/AIDS patients. Methods Totally 177 HIV/AI DS patients were investigated with questionnaire in the epide miological study to collect the data of diagnosis

and the rou tine test of CD4+T lymphocyte count was carried out. Results The young and mid dle-aged females were the most involved group with an increasing incidence in G u angdong Province and with a strong relation of sex and infection route. The main symptoms of the 177 HIV/AIDS patients were fatigue

cough and loss of appetite

the secondary ones were night sweating

skin itching

headache

and hair loss

and the most common sign was skin rash. The leading TCM syndromes were qi and yi n deficiency and lung and kidney deficiency. The distribution of symptoms and si gns

syndromes and various indices was significantly different in gender

age an d infection route （P<0.01）. There showed a strong relation between CD4 and C D8

Th/Ts

WBC

LYM

HGB. The greatest impact on the CD4 was Th/Ts and LYM. Con clusion There was a significant difference in the distribution of sympt oms and signs

syndromes and the lab indices in different gender

age and infection rout e of HIV/AIDS patients in Guangdong province

indicating that the individual tre atment may help to improve the effect. The strong relation between CD4 and CD8

Th/Ts

WBC

LYM

and HGB and the greatest impact of Th/Ts and LYM on CD4 suggest that Th/Ts and LYM can be used as the indices in the evaluation of CD4.