Clinical Observation on 51 Patients with Parkinson’s Disease Treated by Yangjinhua Powder Capsule

SUN Shentian1; WANG Yulin1; WANG Mansu2; HAN Yuedong3; KUANG Haixue4

doi:10.13288/j.11-2166/r.2010.05.029

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Clinical Observation on 51 Patients with Parkinson’s Disease Treated by Yangjinhua Powder Capsule

更新时间：2021-11-17

- Clinical Observation on 51 Patients with Parkinson’s Disease Treated by Yangjinhua Powder Capsule
- Journal of Traditional Chinese Medicine Vol. 51, Issue 5, Pages: 412-415(2010)
- 作者机构：
  
  1. 黑龙江中医药大学附属第二医院针灸五病房
  2. 广州市越秀区第一人民医院
  3. 哈尔滨市现代中医药研究所
  4. 黑龙江中医药大学药学院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2010.05.029
  CLC： R277.7
- Published：2010
- 稿件说明：
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[1]孙申田,王玉琳,王曼苏,韩跃冬,匡海学.洋金花全粉胶囊治疗帕金森病51例临床观察[J].中医杂志,2010,51(05):412-415.

SUN Shentian1, WANG Yulin1, WANG Mansu2, et al. Clinical Observation on 51 Patients with Parkinson’s Disease Treated by Yangjinhua Powder Capsule[J]. Journal of Traditional Chinese Medicine2010, 51(5): 412-415.
[1]孙申田,王玉琳,王曼苏,韩跃冬,匡海学.洋金花全粉胶囊治疗帕金森病51例临床观察[J].中医杂志,2010,51(05):412-415. DOI： 10.13288/j.11-2166/r.2010.05.029.

SUN Shentian1, WANG Yulin1, WANG Mansu2, et al. Clinical Observation on 51 Patients with Parkinson’s Disease Treated by Yangjinhua Powder Capsule[J]. Journal of Traditional Chinese Medicine2010, 51(5): 412-415. DOI： 10.13288/j.11-2166/r.2010.05.029.

摘要

目的观察洋金花全粉胶囊治疗帕金森病的临床疗效。方法51例帕金森病患者中15例首诊患者单纯给予洋金花全粉胶囊

36例已经接受西医治疗的患者在原用药基础上加用洋金花全粉胶囊。分别于用药前、服药7天、服药1个月、3个月及6个月行帕金森病综合评分量表（UPDRS）评分

并评价总体疗效及不良反应。结果51例患者中显著进步29例占56.86%

进步11例占21.57%

稍有进步2例占3.92%

总有效42例

总有效率82.35%。用药7天后

震颤症状改善较为明显（P<0.05）。用药1个月后

UPDRS总评分、UPDRS、UPDRS分量表评分和震颤、肌强直症状改善评分均较治疗前降低

差异有统计学意义（P<0.05或P<0.01）。结论洋金花全粉胶囊可有效改善帕金森病患者的临床症状。

Abstract

Objective To observe the clinical effect of Yangjinhua Powder Capsule（Flos Daturae Powder Capsule）in the treatment of Parkinson’s disease（PD）.Methods Of the 51 PD patients

15 who came for the first visit were administered Yangjinhua Powder Capsule only

and 36 who had been taking western medicine were given Yangjinhua Powder Capsule without stopping using the original medicine.The Unified Parkinson Disease Rating Scale（UPDRS）was used to score the patients before treatment

7 days

3 months

and 6 months after treatment respectively

and as well to evaluate the total effect and untoward reactions.Results After treatment

29（56.86%）patients were remarkably improved;11（21.57%）patients were improved;and 2（3.92%）patients were slightly improved.Totally 42 patients were improved.The total effective rate was 82.35%.After 7 days’ treatment

the improvement of tremor was significant（P<0.05）.After one month’s treatment

the total score of UPDRS

UPDRSⅡ and UPDRSⅢ scores

and tremor and myotonia scores were all significantly improved（P<0.05 or P<0.01）.Conclusion Yangjinhua Powder Capsule is effective in improving the clinical symptoms of PD patients.

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