Objective To observe the clinical effect of Yiaikang Capsule （Herbal capsule for AIDS） combined with treatment based on syndrome differentiation on AIDS patients.Methods Totally 885 AIDS patients from October 2004 to October 2008 were involved in the observation.They were treated with Yiaikang Capsule

5 capsules each time

3 times a day

additionally

treatment based on syndrome differentiation was applied.The treatment course last for 48 months.The scores of symptoms and signs

frequency of common cold

Karnovsky scores

number of CD4+T cell

viral load

and fatality rate were recorded and compared to see the changes after treatment.Results After treatment

the scores of symptoms and signs were significantly lowered

Karnovsky scores and body weight were increased

the frequency of common cold was lower

showing a significant difference in comparing with those before treatment （P<0.01）.Cases with decreased or stabled viral load level was counted 84.8%

the number of CD4+T cell was significantly reduced （P<0.01）

and the fatality rate was getting lower year by year.Conclusion Yiaikang Capsule combined with treatment based on syndrome differentiation can improve symptoms and signs of AIDS patients and reduce opportunistic infections

viral load

and fatality rate.