Systematic Review on the Randomize-Controlled Trials of Perianal Eczema Treated by Chinese Medicine

SHI Chenghe1; CHE Niancong2

doi:10.13288/j.11-2166/r.2010.12.001

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Systematic Review on the Randomize-Controlled Trials of Perianal Eczema Treated by Chinese Medicine

更新时间：2021-11-17

- Systematic Review on the Randomize-Controlled Trials of Perianal Eczema Treated by Chinese Medicine
- Journal of Traditional Chinese Medicine Vol. 51, Issue 12, Pages: 1078-1082(2010)
- 作者机构：
  
  1. 北京大学第三医院中医科
  2. 首都医科大学中医药学院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2010.12.001
  CLC： R275
- Published：2010
- 稿件说明：
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[1]史成和,车念聪.中药治疗肛周湿疹随机对照试验的系统评价[J].中医杂志,2010,51(12):1078-1082.

SHI Chenghe1, CHE Niancong2. Systematic Review on the Randomize-Controlled Trials of Perianal Eczema Treated by Chinese Medicine[J]. Journal of Traditional Chinese Medicine2010, 51(12): 1078-1082.
[1]史成和,车念聪.中药治疗肛周湿疹随机对照试验的系统评价[J].中医杂志,2010,51(12):1078-1082. DOI： 10.13288/j.11-2166/r.2010.12.001.

SHI Chenghe1, CHE Niancong2. Systematic Review on the Randomize-Controlled Trials of Perianal Eczema Treated by Chinese Medicine[J]. Journal of Traditional Chinese Medicine2010, 51(12): 1078-1082. DOI： 10.13288/j.11-2166/r.2010.12.001.

摘要

目的用系统评价方法评价中药治疗肛周湿疹的疗效和安全性。方法通过互联网检索期刊数据库PubMed、Cochrane library、CNKI、VIP、CBM、CMCI。纳入的临床试验类型为中药或者中药联合西药与单纯使用西药治疗肛周湿疹比较的随机对照试验。采用Cochrane协作网的质量评价标准并用其提供的软件RevMan4.2

对纳入试验的临床总有效率、症状改善情况及不良反应进行统计分析。结果共计纳入32篇随机对照试验治疗3429名患者。所纳入的文献质量普遍偏低。26个中药与西药治疗比较的试验中有15个研究结果显示试验组疗效优于对照组

11个研究显示两组统计结果差异无统计学意义;6个中药联合西药与单用西药治疗比较的试验中有5个研究结果显示试验组疗效优于对照组

1个研究显示两组结果无统计学意义。从干预措施整体比较

中药及中药联合西药治疗肛周湿疹临床总有效率及症状改善情况优于单用西药治疗。中药治疗肛周湿疹未发现明显不良反应。结论中药治疗肛周湿疹可能具有较好的疗效

但方法学方面亟待提高。

Abstract

Objective To evaluate the effect and safety of Chinese medicine for perianal eczema with the method of systematic review.Methods The database such as Pubmed

Cochrane library

CNKI

VIP

CBM and CMCI were consulted through internet.The quality evaluation standard of Cochrane Collaboration was adopted and the software RevMan 4.2 provided was used for the statistical analysis of the clinical total effective rate

symptom improvement

and untoward reactions of the trials involved.Results There were 32 randomized control trials（3429 patients）reviewed.All trials involved were of low quality.Of the 26 trials of Chinese medicine in comparison with western drugs

15 ones showed that the therapeutic effect of the experimental group was better than the control group

and 11 ones showed that there was no significant difference between the two groups.Of the 6 trials of Chinese medicine combined with western drugs in comparison with western drugs only

5 ones showed that the therapeutic effect of the experimental group was better than the control group

and one trial showed that there was no significant difference between the two groups.The comparison of intervention measures on the whole

the clinical total effective rate and symptom improvement of the Chinese medicine and Chinese medicine combined with western drugs were better than those of the western drugs only.There was no obvious adverse effect reported in the trials of Chinese medicine treatment.Conclusion Chinese medicine is effective in improving symptoms of eczema patients but methodology needs to be improved urgently.

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