Objective To study the correlation between TCM syndrome scores and celluar immune status of the type Ⅱ diabetes patients with angiopathy of lower limbs who were differentiated as qi and yin deficiency accompanied with blood stasis syndrome.Methods Based on the grading criteria of TCM syndrome scores

the 74 patients enrolled were divided into mild

medium

and severe groups and 10 healthy volunteers were taken as the control group.The changes in CD4

CD4%

CD8

CD8%

and CD4/CD8 were observed and the correlation between CD4

CD8 and TCM syndrome scores was analyzed.Results Of the three groups

there was statistical difference in age between the mild and severe groups（P<0.05）

and there was statistical difference in the time of diagnosing diabetes between the mild and severe groups and between the medium and severe groups（P<0.05）.There was statistical difference in CD4

CD8

and CD4% among the 3 groups（P<0.05）.CD4 was negatively correlated with the scores of qi deficiency syndrome

blood stasis syndrome

and the time of diagnosing diabetes（P<0.05）

but was not related with the scores of yin deficiency syndrome

and the age of patients.CD8 was positively correlated with the scores of yin deficiency syndrome and blood stasis syndrome（P<0.05）

but was not related with the scores of qi deficiency syndrome

age of patients

and the time of diagnosing diabetes（P>0.05）.Conclusion The CD4 decrease and CD8 increase are the important characteristics of celluar immune status of type Ⅱ diabetes patients with angiopathy of lower limbs in qi and yin deficiency accompanied with blood stasis syndrome

and they are related with the qi deficiency and blood stasis.Qi and yin dysfunction and the severity of blood stasis exert influence on the celluar immune status of the body.