Objective To evaluate the indicated TCM syndromes of Shanggan Granules （Granule for upper respiratory tract infection） in the treatment of fever of viral upper respiratory tract infection.Methods Totally 433 viral upper respiratory tract infection patients were collected from the 8 centers.They were diagnosed into 5 syndromes

including wind cold

wind heat

weifen and qifen diseased simultaneously

wind attacking the exterior -uncertain cold or heat

and wind attacking the exterior - cold and heat in complication.All were administered Shanggan Granules

one dose per day in case the body temperature was below 39.0℃

two doses per day if the body temperature was over 39.0℃

for 3 days in succession.The regional distribution of every syndrome

instant antifebrile function

antifebrile time

and comprehensive curative effect were observed.Results Body termperature of every syndrome group 2h

3h

and 4h after medication was statistically different from before medication （P<0.05 or P<0.01）

and the effect starting-time of every syndrome group was not statistically different from each other （P>0.05）.Compared with the wind cold syndrome

the antifebrile time of wind heat and weifen and qifen diseased simultaneously syndromes was statistically different （P<0.05）.The clinical cure rate of the syndrome wind attacking the exterior - cold and heat in complication and the syndrome weifen and qifen diseased simultaneously syndromes was the highest

statistically different from that of the syndrome wind cold and wind attacking the exterior -uncertain cold or heat （P<0.05 or P<0.01）.Conclusion Shanggan Granules is effective for all the above-mentioned five syndromes

of the viral upper respiratory tract infection fever patients

especially good for those with the syndromes of cold and heat in complication

weifen and qifen diseased simultaneously

and wind heat.