Objective To observe the influence of electro-acupuncture at different points on norepinephrine （NE） in the paraventricular nucleus region of hypothalamus of myocardial ischemic rats. Methods Ten of the eighty SD rats were randomly selected as normal group

and the others were made myocardial ischemia models by ligating the prone descending branch of coronary artery. The 40 successfully made models were randomized into model group

Shenmen （HT 7） group

Neiguan （PC 6） group

and Taiyuan （LU 9） group

with 10 in each. Three days after modeling

the electro-acupuncture groups began to have electro-acupuncture

10min each time

once per day

for 3 days. Then

the brain tissues 2mm×2mm×2mm of the paraventricular nucleus region of hypothalamus were taken out for measuring the NE content with the ELISA method. Results In the model group

the NE content in the paraventricular nucleus region of hypothalamus was significantly decreased than that in the normal group （P<0.01）. In the electro-acupuncture groups

it was all increased than that in the model group （P<0.05 or P<0.01）

of which

the NE content in the Shenmen （HT 7） group was higher than that in both Neiguan （PC 6） group and Taiyuan （LU 9） groups （P<0.05 or P<0.01）

and it was higher in the Neiguan （PC 6） group than in the Taiyuan（LU 9） group （P<0.05）. Conclusion Electro-acupuncture at Shenmen （HT 7）

Neiguan （PC 6）

and Taiyuan （LU 9） is all effective in promoting the release of NE in the paraventricular nucleus region of hypothalamus

benefiting the improvement of heart functions. The effect of electro-acupuncture at Shenmen （HT 7） is the best

while that of electro-acupuncture at Neiguan （PC 6） and Taiyuan （LU 9） is the second.