Therapeutic Effect of Jinyinhua Soft Gelatin Capsule Combined with Kangfuxin Liq uid for Herpangina

LI Huizhu; LAN Xiucong; ZHENG Guiai

doi:10.13288/j.11-2166/r.2012.09.004

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Therapeutic Effect of Jinyinhua Soft Gelatin Capsule Combined with Kangfuxin Liq uid for Herpangina

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- Therapeutic Effect of Jinyinhua Soft Gelatin Capsule Combined with Kangfuxin Liq uid for Herpangina
- Journal of Traditional Chinese Medicine Vol. 53, Issue 9, Pages: 758-760(2012)
- 作者机构：
  
  丽水市人民医院儿科
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2012.09.004
  CLC： R276.1
- Published：2012
- 稿件说明：
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[1]李慧竹,兰秀聪,郑桂爱.金银花软胶囊联合康复新液治疗疱疹性咽峡炎105例疗效观察[J].中医杂志,2012,53(09):758-760.

LI Huizhu, LAN Xiucong, ZHENG Guiai. Therapeutic Effect of Jinyinhua Soft Gelatin Capsule Combined with Kangfuxin Liq uid for Herpangina[J]. Journal of Traditional Chinese Medicine2012, 53(9): 758-760.
[1]李慧竹,兰秀聪,郑桂爱.金银花软胶囊联合康复新液治疗疱疹性咽峡炎105例疗效观察[J].中医杂志,2012,53(09):758-760. DOI： 10.13288/j.11-2166/r.2012.09.004.

LI Huizhu, LAN Xiucong, ZHENG Guiai. Therapeutic Effect of Jinyinhua Soft Gelatin Capsule Combined with Kangfuxin Liq uid for Herpangina[J]. Journal of Traditional Chinese Medicine2012, 53(9): 758-760. DOI： 10.13288/j.11-2166/r.2012.09.004.

摘要

目的观察金银花软胶囊联合康复新液治疗儿童疱疹性咽峡炎的临床疗效。方法选择315例疱疹性咽峡炎患儿随机分为对照组、单一治疗组和联合治疗组各105例

对照组给予利巴韦林冲剂

每天3次;单一治疗组给予金银花软胶囊

每次1～2粒

每天3次

同时给予康复新液口腔内含服

每次0.5～2ml

每天3～5次;联合治疗组同时给予利巴韦林冲剂、金银花软胶囊联合康复新液治疗

3组疗程均为1周。观察各组患儿退热时间、疱疹消退时间及临床疗效。结果联合治疗组退热时间、疱疹消退时间明显短于对照组和单一治疗组

比较差异有统计学意义（P<0.05）;对照组、单一治疗组、联合治疗组总有效率分别为85.7%、87.6%、97.1%

单一治疗组总有效率与对照组比较差异无统计学意义（P>0.05）

联合治疗组总有效率明显优于对照组和单一治疗组（P<0.05）。结论金银花软胶囊联合康复新液治疗疱疹性咽峡炎临床疗效明显

与利巴韦林冲剂联合使用疗效更佳。

Abstract

Objective To observe the therapeutic effect of Jinyin hua soft gelatin c apsule [soft gelatin capsule of Jinyinhua（Flos Lonicerae Japonicae）] combined w ith Kangfuxin liquid（liquid of Americana Linn） for pediatric herpangina

Methods Totally 315 children suffered from herpangina were randomized into control group

monotherapy group and combination therapy group

wit h 105 in each.The control group was given ribavirin granule three times daily

The monotherapy group was given Jinyinhua soft gelatin capsule

taken 1 to 2 cap s each time

3 times daily

combined with 0.5ml to 2ml of Kangfuxin liquid

3 to 5 times daily.The combination therapy group was given ribavirin granule

Jinyin hua soft gelatin capsule and Kangfuxin liquid.The treatment course lasted for 1 week.The defervesce time

the time of disappearance of herpes and the therapeu tic effect were observed.Results The time of defervesce and disappearance of her pes in the combination therapy group was significantly shorter than that in the control group and monotherapy group（P<0.05）.The total effective rate of the control group

monotherapy group and combination therapy group was 85.7%

87.6% and 97.1%

respectively.The difference between the monotherapy group and the control group was not statistically s ignificant（P>0.05）.The total effective rate of the combination group was superior to those of the other two groups（P<0.05）.Conclusion The combination therap y of Jinyinhua soft gelatin capsule and Kangfuxin liquid is effective for herpan gina

especially when combined with ribavirin

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