Objective To observe the long term effect of strength ening vital qi

trans forming phlegm and clearing heat for stable bronchiectasis.Methods One hundred cases of stable bronchiectasis from three clinical centers were randomized into the control group and Chinese medication group

with 50 in each.The control gro up was treated with conventional western medication including sputum drainage and short term use of antibiotics

while Zhikuo Wending Formul a（formula for bronchiectasis） was added in the Chinese medication group.One ye ar after the treatment

the frequency of acute exacerbations

scores from the St George’s Respiratory Questionnaire（SGRQ） and pulmonary function parameters wer e observed and compared.Results After treatment

the annual fre quency of acute exacerbations in the Chinese medication group decreased significantly（P<0.01）

with significant difference between that in the control group（P<0.01）.The SGRQ in symptom

activity

psychology and total score in the Chinese medication group decreased significantly after treat ment（P<0.05 or P<0.01）

with significant difference between those in the contro l group except symptom score（P<0.01）.After treatment

forced vital capacity（FVC）

F VC%

forced expiratory volume 1（FEV1） and FEV1% decreased significantly in the control group（P<0.05）.The decline of FVC

FEV1 and FEV1% in the Chinese medica tion group was not significant（P>0.05） except FVC%（P<0.05）.The value of FEV1 in the Chinese medication group was stable with significant difference between t he control group（P<0.05）.The decline rates of FEV1 and FEV1% in the Chinese me dication group were significantly lower than those in the control group（P<0.01）.Conclusion The therapy of strengthening vital qi

transforming phlegm and clea ring heat is effective and safe for bronchiectasis.It could reduce the annual frequency of acute exacerbations

improve the quality of life

slow down the decline of FEV1

and improve long term efficay.