Clinical Research on Chinese Medication for 311 Cases of AIDS-Related Chronic Diarrhea

TIAN Ming1; ZHANG Wei1; NI Liang1; XU Liran2; ZHANG Mingli3; GUO Changhe4; TAN Xinghua5; CEN Yuwen5; HUANG Kui6; SUN Lijun7; GAO Hui8; CHEN Jianhua9; LIU Jingyuan1; ZHOU Yuling1; WAN Gang1; HUA Wenhao1; WANG Huizhu1; WANG Rongbing1; WANG Yuguang10

doi:10.13288/j.11-2166/r.2012.12.019

您当前的位置：

首页 >

文章列表页 >

Clinical Research on Chinese Medication for 311 Cases of AIDS-Related Chronic Diarrhea

更新时间：2021-11-17

- Clinical Research on Chinese Medication for 311 Cases of AIDS-Related Chronic Diarrhea
- Journal of Traditional Chinese Medicine Vol. 53, Issue 12, Pages: 1016-1019(2012)
- 作者机构：
  
  1. 首都医科大学附属北京地坛医院
  2. 河南中医学院第一附属医院
  3. 河南省中医药研究院附属医院
  4. 河南省上蔡县中医院
  5. 广州市第八人民医院
  6. 广西壮族自治区龙潭医院
  7. 北京佑安医院
  8. 新疆维吾尔自治区传染病医院
  9. 昆明市第三人民医院
  10. 首都医科大学附属北京中医医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2012.12.019
  CLC： R259
- Published：2012
- 稿件说明：
移动端阅览
[1]田明,张伟,倪量,徐立然,张明利,郭长河,谭行华,岑玉文,黄葵,孙丽君,高辉,陈建华,刘景院,周玉玲,万刚,华文浩,王慧珠,王融冰,王玉光.中医药治疗艾滋病相关性慢性腹泻患者311例临床研究[J].中医杂志,2012,53(12):1016-1019.

TIAN Ming1, ZHANG Wei1, NI Liang1, et al. Clinical Research on Chinese Medication for 311 Cases of AIDS-Related Chronic Diarrhea[J]. Journal of Traditional Chinese Medicine2012, 53(12): 1016-1019.
[1]田明,张伟,倪量,徐立然,张明利,郭长河,谭行华,岑玉文,黄葵,孙丽君,高辉,陈建华,刘景院,周玉玲,万刚,华文浩,王慧珠,王融冰,王玉光.中医药治疗艾滋病相关性慢性腹泻患者311例临床研究[J].中医杂志,2012,53(12):1016-1019. DOI： 10.13288/j.11-2166/r.2012.12.019.

TIAN Ming1, ZHANG Wei1, NI Liang1, et al. Clinical Research on Chinese Medication for 311 Cases of AIDS-Related Chronic Diarrhea[J]. Journal of Traditional Chinese Medicine2012, 53(12): 1016-1019. DOI： 10.13288/j.11-2166/r.2012.12.019.

摘要

目的观察中医药治疗艾滋病相关性慢性腹泻的疗效及安全性。方法采用多中心、对照的临床研究方法

所有入组病例均进行大便病原学检查

对其中240例进行电子结肠镜检查

将311例艾滋病慢性腹泻患者辨证分为健脾祛湿治疗组（健脾止泻颗粒）102例、补肾固涩治疗组（泻痢康胶囊）106例及对照组（盐酸洛哌丁胺胶囊）103例。疗程均为2周

观察治疗前后各组患者腹泻量表积分、大便频次变化和慢性腹泻临床有效率。结果艾滋病慢性腹泻病原学阴性者263例占84.57%

而病原学阳性者中隐孢子虫32例。治疗2周后

健脾祛湿治疗组、补肾固涩治疗组与对照组腹泻量表积分差异均有统计学意义（P<0.05）;治疗1周后与治疗2周后各组大便频次均较治疗前下降（P<0.05）。结论健脾祛湿与补肾固涩为主两种治疗方案治疗艾滋病相关性慢性腹泻均可改善患者症状

减少每日大便频次

明显提高慢性腹泻临床有效率。

Abstract

Objective To observe the therapeutic effect and safety of Chinese medication on acquired immune deficiency syndrome（AIDS）-related chronic diarrhea.Methods The multi-center controlled clinical trial was conducted.Patients with AIDS-related chronic diarrhea were randomized to the treatment group A

the treatment group B and the control group.The treatment group A of 102 cases was given Jianpi Zhixie Granules（Spleen-Fortifying Antidiarrheal Granules） and the treatment group B of 106 cases was given Xielikang Capsule（antidiarrheal capsule）.The control group of 103 cases was given Loperamide Hydrochloride Capsules.The treatment course lasted for 2 weeks.The diarrhea scale scores

stool frequency changes and the clinical control of chronic diarrhea rates were observed in all groups before and after treatment.All enrolled patients were checked for stool specimens of the etiology and 240 patients for electronic colonoscopy.Results The etiological negativity accounted for 84.57%（263/311） in the AIDS-related patients.Of the etiologically positive cases

32 cases were cryptosporidium infection.After 2 weeks of treatment

the diarrhea scale scores were significantly decreased in both treatment groups（P<0.05）.The stool frequency and total effective rates in the treatment groups were improved significantly after treatment（P<0.05）.Conclusion Jianpi Zhixie Granules and Xielikang Capsule could relieve the symptoms

reduce the daily stool frequency and improve the effective rate for AIDS-related chronic diarrhea.

关键词

Keywords

references

查看原文

Views

479

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Strategies for Promoting Immune Reconstitution in HIV/AIDS Patients by Traditional Chinese Medicine

Effect of Shenfu Injection on Advanced Acquired Immune Deficiency Syndrome Model Rhesus

Relation between Peripheral Blood T lymphocyte Subsets and Chinese Medicine Syndrome in HIV/AIDS Patients

Distribution and Development Rules of Chinese Medicine Syndromes in 2237 Cases of HIV/AIDS

Establishment of Basic Theory of Acquired Immune Deficiency Syndrome in Traditional Chinese Medicine

Related Author

LIU Ying

MA Chong

ZHANG Hongqi

HU Dongren

LI Maoqing

FU Linchun

HU Yingjie

ZHANG Miaomiao

Related Institution

Research Center of AIDS Treatment with Traditional Chinese Medicine, China Academy of Chinese Medical Sciences

Institute of Basic Theory for Chinese Medicine，China Academy of Chinese Medical Sciences

Institute of Tropical Medicine,Guangzhou University of Chinese Medicine

China Academy of Chinese Medical Sciences

The 8th People’s Hospital of Guangzhou City

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰