Objective To observe the attenuation and synergy effects of auricular acupressure therapy for moderate to severe cancer pain. Methods One hundred cases of moderate to severe cancer pain were randomized into treatment group and control group

with 50 in each. The control group was given Oxycontin orally and the treatment group was combined with the auricular acupressure therapy. The analgesic response rate

dosage and the incidence and extent of nausea

vomiting and constipation of both groups were observed 7 days later. Results There was no significant difference in the analgesic response rate between groups （P>0.05）. The dosage of Oxycontin in the treatment group was significantly lower than that in the control group （P<0.05）. The incidence of nausea

vomiting and constipation in the treatment group was significantly lower than that in the control group （P<0.05）. Conclusion The auricular acupressure therapy combined with strong opioids is effective for moderate to severe cancer pain

especially in reducing the dosage of strong opioids and digestive toxicity.