Objective To investigate the clinical value of traditional Chinese medicine（TCM） therapy for type 2 diabetes with poor glycemic control.Methods Totally 138 type 2 diabetes patients with poor glycemic control were divided into the TCM therapy group

insulin therapy group and the combo therapy group according to the willingnese and baseline data of the patients

with 46 in each.The corresponding therapy was given to each group respectively for 8 weeks.The levels of fasting blood glucose（FPG）

2-hour postprandial blood glucose（2hPG） and glycosylated hemoglobin（HbAc1） were detected.The frequency of hypoglycemia

body weight

blood pressure

serum lipids and TCM symptom scores were observed before and after treatment.The frequency of common symptoms related to liver depression qi stagnation and phlegm stasis were compared among the three groups before and after treatment.Results After 8 weeks of treatment

the average decline of HbAc1 was 0.60%

1.50% and 1.78% in the TCM therapy group

insulin therapy group and combo therapy group respectively.The average decline of FPG was 1.1mmol/L

2.8mmol/L and 3.1mmol/L respectively.The average decline of 2hPG was 2.6mmol/L

4.5mmol/L and 5.8mmol/L respectively.The three glycemic index decreased significantly in the TCM therapy group as compared with other two groups（P<0.05）.Comparing with the insulin therapy group

low-density lipoprotein C（LDL-C）

TCM symptom scores and the frequency of common symptoms decreased significantly in TCM therapy group and combo therapy group（P<0.05）.The combo therapy could significantly decrease the average daily insulin dosage and the frequency of hypoglycemia

with statistical difference between the insulin therapy group（P<0.05）.Conclusion As a therapy for type 2 diabetes with poor glycemic control

TCM therapy is not good at controlling the glycemic level as compared with insulin.However

it could obviously improve the serum lipid level

relieve the symptoms

and prevent hypoglycemia as combined with insulin.