Objective To evaluate the efficacy and safety of Lon gbi Xintong Granule（granule for dysuria） for chronic prostatitis patients with damp-heat and bloo d-stasis syndrome.Methods A multicenter

randomized do uble blind

placebo parall eled controlled clinical trial was conducted.Totally 240 chronic prostatitis pa tients with damp-heat and blood-stasis syndrome were randomized into the small-d ose trial group

large-dose trail group and placebo control group

with 80 in e a ch.The small-dose trial group was given one packet of Longbi Xintong Granule（8 g per packet） and one packet of placebo per time

twice daily.The large-dose t r ail group was given two packets of Longbi Xintong Granule（8g per packet） per ti me

twice daily.The placebo control group was given two packets of placebo per time

twice daily.The treatment lasted for 4 weeks.The National Institutes of Health Chronic Prostatitis Symptom Index（NIH-CPSI）

efficacy of Chinese medica l syndrome

total score of Chinese medical symptoms and adverse reactions were ob served.Results After treatment

the NIH-CPSI

total s cores of Chinese medical s ymptoms and total effective rates in two trail groups were superior to those in the placebo group（P<0.05）

but there was no significant difference between two trail groups（P>0.05）.The symptoms in two trail groups were significantly r elieved as compared with the placebo group（P<0.05）

but there was no signi fican t dif ference between two trail groups（P>0.05）.Conclusion Longbi Xintong Granule is safe and effective for chronic prostatitis with damp-heat and blood-stasis syn d rome

with no significant difference between large dose and small dose（P>0.05）.