Objective To observe the therapeutic effect of radiotherapy combined with Chinese medicine enema on radiation enteritis.Methods Eighty-nine patients with locally advanced cancer were randomized into the Chinese medication （ radiother- apy+oral Chinese medicine+ Chinese medicine enema ） group of 47cases and western medication （ radiotherapy+oral west- ern medicine+ western medicine enema ） group of 42cases.For the Chinese medication group

Gegen Qinlian Decoction and Baitouwong Decoction were used for enema after radiotherapy each day

meanwhile

oral medication based on syndrome differ- entiation was given.Normal saline added with smecta and Dexamethasone was given to the Western medication group for ene- ma

once everyday after radiotherapy

and smecta and levofloxacin were given orally when diarrhea appeared.The intestinal a- cute radiation injury degree and quality of life in both groups were observed after treatment.Results The incidence of acute ra- diation enteritis above gradeⅡin the Chinese medication group was significantly less than that in the western medicine group （ P<0.05 ） .Patients with KPS score above 80points was significantly more in the Chinese medication group than in the west- ern medication group （ P<0.05 ） .Conclusion Chinese medicine oral medication and enema for radiation enteritis could obvi- ously reduce the incidence of acute radiation enteritis and effectively improve the quality of life of patients.