Objective To observe the effect of New Xuefu Zhuyu Soft Capsule（Blood Stasis-Expelling Soft Capsule）on the blood stasis syndrome

lipid peroxidation and vascular endothelial inflammation in patients with coronary heart disease（CHD）.Methods Two hundred cases of CHD were randomized into the treatment group and control group

with 100in each.Both groups were given conventional western medicine for 6months.The treatment group was added with New Xuefu Zhuyu Soft Capsule orally

2g each time

3times daily.The signs of blood stasis syndrome

carotid artery intima-media thickness（cIMT）

oxidized low density lipoprotein（ox-LDL）

high sensitivity C-reactive protein（hs-CRP）and serum OX40Lwere observed before and after treatment.Results The signs of blood stasis syndrome in both groups were relieved after treatment.The effective rate of the treatment group and the control group was 83.1%and 60.9%respectively

with significant difference between groups（P<0.05）.The level of ox-LDL

hs-CRP and OX40L was significantly decreased in both groups after treatment（P<0.05）

especially in the treatment group（P<0.05）.There was no significant difference in cIMT between groups and in group（P>0.05）.Conclusion New Xuefu Zhuyu Soft Capsule for CHD could relieve signs of blood stasis syndrome

inhibit lipid peroxidation and anti-vascular endothelial inflammation.