Objective To observe the efficacy and effect of Chinese medicine into the gas stream diffusion method on the food intolerance（FI）state of patients with ulcerative colitis（UC）.Methods Fifty-four UC patients were randomized into trail group and control group

with 27in each.The trail group was given Chinese medicine into the gas stream diffusion method with 200ml of Qihuang Changkang Liquid[liquid of huangqi（Radix Astragali）

huanglian（Rhizoma Coptidis）and huangbo（Cortex Phellodendri Chinensis）for UC]

once daily.The control group was given 1.0g of sulfasalazine tablets

4times daily.One treatment course lasted for one month and the treatment lasted for 3courses.The clinical symptoms were scored before treatment and after 1month and 3months of treatment respectively.FI serum specific IgG antibody was detected

inflammation degree in the colonoscopy was scored according to Baron’s classification and the Southerland disease activity index（DAI） was scored before and after treatment.Results The total effective rate of the trail group and control group was 85.19%and 76.00%respectively

with no significant difference between groups（P>0.05）.The scores of diarrhea

mucus

blood and pus and abdominal pain were significantly decreased in both groups after 1month and 3months of treatment（P<0.05）.The symptom scores in the trail group were significantly lower than those in the control group after 3months of treatment（P<0.05）.The positive rate of FI serum specific IgG antibody was significantly decreased in the trail group after treatment（P<0.05）.The difference in Baron’s scores and Southerland DAI scores before and after treatment was significant in both groups（P<0.05）.Conclusion Chinese medicine into the gas stream diffusion method is effective for UC and could effectively regulate the food intolerance state of patients.