Objective To observe the therapeutic effect of treatment based on three syndrome types divided by Prof.XU Jingfan for chronic atrophic gastritis （C AG） with precancerous lesions and its effect on quality of life （Q OL） .Methods Totally 186cases of CAG with precancerous lesions were divided into three syndrome types

i.e.center-deficiency qi-stagnation syndrome（ 86cases）

liver-stomach disharmony syndrome （7 0cases） and stomach-yin deficiency syndrome （3 0cases） .Three kind of relevant Chinese medications were used for patients with different syndrome types respectively for 6months.The clinical efficacy

gastroscope

pathological efficacy and Chinese medicine-spleen-stomach patients reported outcomes sacle （ CM-SSPRO ） were observed before and after treatment.Results The total effective rate of center-deficiency qi-stagnation syndrome

liver-stomach disharmony syndrome and stomach-yin deficiency syndrome was 89.54%

92.85% and 70.00% respectively

with a significant difference between syndrome types （ P<0.05 ） .There were no significant differences in efficacy of gastroscope

glandular atrophy

intestinal metaplasia

and the glandular dysplasia between syndrome types of center-deficiency qi-stagnation syndrome

liver-stomach disharmony syndrome and stomach-yin deficiency syndrome4 （ P>0.05 ） .The scores of physiology

psychology

independence

social environment and CM-SSPRO were significantly decreased after treatment （ P<0.05 ）

but with no significant difference between syndrome types （ P>0.05 ） .Conclusion The treatment based on three syndrome types divided by Prof. XU Jingfan could obviously improve the clinical efficacy

gastroscope

patholog and QOL for CAG with precancerous lesions.