Objective To observe the effect of Chinese medication on immune function and chronic airway inflammation in asthma children at chronic duration stage.Methods Seventy children with bronchial asthma at chronic duration stage were randomized into the treatment group and control group

with 35in each.The treatment group was given TaizijianⅡformula （ empirical formula of Prof.YU Jingmao ）

one dose daily

twice orally.The control group was given 5mg of singulair

o nce every night.The treatment course lasted for 3months.The frequency of asthma attack and respiratory infection

child asthma control test （ C-ACT ）s cores

urine leukotriene E 4 （L TE 4 ）

salivary secretory immunoglobulin A （ sIgA ）

traditional Chinese medicine（ TCM） syndrome scores and comprehensive efficacy were observed and determined before and after treatment.Results The total effective rate of the treatment group and control group was 96.88%and 96.97%respectively

with no significant difference between groups （ P>0.05 ） .There was no significant difference in TCM syndrome scores in the control group after treatment （ P>0.05 ） .The TCM syndrome scores in the treatment group were significantly decreased after treatment （ P<0.001 ）

with a significant difference between groups （ P<0.001 ） .The frequency of asthma attack and the level of urine LTE 4 decreased significantly in both groups after treatment （ P<0.01or P<0.001 ）

with no significant difference between groups in the frequency of asthma attack （ P>0.05 ）

but with a significant difference in the level of urine LTE 4 （ P<0.01 ）. The frequency of respiratory infection decreased significantly in the treatment group after treatment （ P<0.01 ）

with a significant difference between groups （ P<0.05 ） .The C-ACT scores and peak expiratory flow （P EF） %increased significantly in both groups after treatment （ P<0.001 ）

with no significant difference between groups （ P>0.05 ） .The level of salivary sIgA was significantly increased in the treatment group after treatment （ P<0.001 ）

with a significant difference between groups （ P<0.001 ） .Conclusion Chinese medication could enhance the immune function and relieve the chronic airway inflammation for child asthma at chronic duration stage.