Objective To observe the therapeutic effect and safety of Duhuo Jisheng Decoction（Pubescent Angelica and Mistletoe Decoction）for lumbar disc herniation.Methods PubMed

China National Knowledge Internet

VIP database

China Biology Medicine disc and Chinese Medical Current Contents were searched.The randomized clinical trials of Duhuo Jisheng Decoction or combined with other therapies such as traction

acupuncture

massage

cupping and western medicine treatment were included as compared with other therapies.The data was extracted according to the data extraction form and the data was analyzed with the quality evaluation criteria of the Cochrane Collaboration and software RevMan5.1.The outcome was evaluated according to the relief rate of clinical symptoms

analog visual scale（VAS）and adverse reactions.Results Totally 29articles and 3179 patients were included.All included articles were of low quality.There were significant differences between other therapies and Duhuo Jisheng Decoction or combined with other therapies in the relief rates of clinical symptoms and VAS scores （P<0.05or P<0.01）.There was no obvious adverse reaction reported in the trials of Duhuo Jisheng Decoction.Conclusion Duhuo Jisheng Decoction or combined with other therapies could relieve the clinical symptoms for patients with lumbar disc herniation.The experimental study methodology needs to be improved.