Objective To research the relationship between tongue fur

serum epidermal growth factor（EGF）and laboratory parameters in gastric cancer patients.Methods Totally 266 cases of gastric cancer and 246 cases of normal control population were included and divided into the gastric cancer group and control group.The serum EGF was detected

the tongue fur was observed and the laboratory parameters such as white blood cell count

neutrophils

lymphocytes

monocytes

total protein

aspartate aminotransferase and blood glucose were recorded.The relationship between tongue fur

serum EGF and laboratory parameters was analyzed.Results The highest percentage of thick tongue fur was 51.5% in the gastric cancer group. The highest percentage of thin tongue fur was 64.6% in the control group.The percentage of thin tongue fur was decreased and the percentage of thick tongue fur was increased in the gastric cancer patients with abnormal white blood cell count

lymphocytes and total protein（P<0.01）.The serum EGF was significantly increased in the gastric cancer group as compared with the control group（P<0.01）.The serum EGF was significantly increased in both groups when total protein decreasing as compared with the normal（P<0.01）.Correlation analysis showed that the total protein were negatively correlated with serum EGF（P<0.01）.Conclusion The abnormality of white blood cells

lymphocytes and total protein is closely related with the tongue fur and serum EGF in gastric cancer patients.