MENG Fanhong, LI Ming, LI Jinghua, et al. Mining the Medication Law of Ancient Analgesic Formulas Based on Complex Network[J]. Journal of Traditional Chinese Medicine2013, 54(2): 145-148.
MENG Fanhong, LI Ming, LI Jinghua, et al. Mining the Medication Law of Ancient Analgesic Formulas Based on Complex Network[J]. Journal of Traditional Chinese Medicine2013, 54(2): 145-148.DOI: 10.13288/j.11-2166/r.2013.02.025.
Mining the Medication Law of Ancient Analgesic Formulas Based on Complex Network
composition law and medication characteristics of the ancient analgesic formulas through data mining in complex network and provide a reference for treating pain and new drug development.Methods Totally 2 746 formulas were selected from 14 typical formulary books during the Han to Jin-Yuan Dynasties.The analgesic formula database was established and the terms were standardized.The complex network of analgesic formulas was built according to the scale-free networks law of formula composition and the core medicinal and composition law was analyzed.Results The top 10 frequent single herbs and couplet medicines during the Han
Tang
Song
Jin and Yuan Dynasties were found according to the pain location such as abdominal pain
chest pain
heartache
headache
limb pain
lower back pain
hypochondriac pain
eyes pain
sore throat
body aches and tooth pain.Conclusion The core medicinal
composition law and medication characteristics of analgesic formulas during the Han
Tang
Song
Jin and Yuan Dynasties are found through data mining in complex network.This research plays an exemplary role in digging the medication and composition law of ancient analgesic formulas in future.
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