Effect of Supplemented Wuzi Yanzong Decoction on the Quality of Sperm and Secretion of Seminal Fructose

CHEN Dong1; ZHONG Jian1; CHEN Shuren2; ZHANG Yuejuan1; ZHANG Wenrong1; WANG Gangwei1; Ma Jiyuan1

doi:10.13288/j.11-2166/r.2013.05.013

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Effect of Supplemented Wuzi Yanzong Decoction on the Quality of Sperm and Secretion of Seminal Fructose

更新时间：2021-11-17

- Effect of Supplemented Wuzi Yanzong Decoction on the Quality of Sperm and Secretion of Seminal Fructose
- Journal of Traditional Chinese Medicine Vol. 54, Issue 5, Pages: 401-404(2013)
- 作者机构：
  
  1. 暨南大学附属第一医院
  2. 南方医科大学附属中西医结合医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2013.05.013
  CLC： R277.5
- Published：2013
- 稿件说明：
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[1]陈栋,钟键,陈恕仁,章岳娟,张文容,王刚伟,马继远.加味五子衍宗汤对男性精子质量及精浆果糖分泌的影响[J].中医杂志,2013,54(05):401-404.

CHEN Dong1, ZHONG Jian1, CHEN Shuren2, et al. Effect of Supplemented Wuzi Yanzong Decoction on the Quality of Sperm and Secretion of Seminal Fructose[J]. Journal of Traditional Chinese Medicine2013, 54(5): 401-404.
[1]陈栋,钟键,陈恕仁,章岳娟,张文容,王刚伟,马继远.加味五子衍宗汤对男性精子质量及精浆果糖分泌的影响[J].中医杂志,2013,54(05):401-404. DOI： 10.13288/j.11-2166/r.2013.05.013.

CHEN Dong1, ZHONG Jian1, CHEN Shuren2, et al. Effect of Supplemented Wuzi Yanzong Decoction on the Quality of Sperm and Secretion of Seminal Fructose[J]. Journal of Traditional Chinese Medicine2013, 54(5): 401-404. DOI： 10.13288/j.11-2166/r.2013.05.013.

摘要

目的观察加味五子衍宗汤治疗男性不育症患者的疗效和对精子质量、精浆成分的影响。方法将192例精子活力低下所致男性不育患者随机分为治疗组97例和对照组95例

治疗组给予加味五子衍宗汤

每日1剂;对照组给予六味地黄丸

每次6g

每日3次

两组均以3个月为1个疗程。观察两组临床疗效

并测定两组治疗前后精子活动率、精子活动力、精浆果糖及精浆中性α-糖苷酶的水平。结果治疗组总有效率为81.44%

对照组总有效率为57.89%

治疗组明显优于对照组（P<0.01）。两组治疗后精子活动率、精子活动力均较治疗前明显提高（P<0.05或P<0.01）

治疗组提高的更为显著（P<0.05）。治疗组治疗后精浆果糖定量、中性α-糖苷酶水平与治疗前比较差异均有统计学意义（P<0.05）。结论加味五子衍宗汤能有效改善精子活动质量

增加生殖系统附属性腺分泌果糖。

Abstract

Objective To observe the effect of Supplemented Wuzi Yanzong Decoction （Supplemented Five-Seed Progeny Decoction） on sperm motility and secretion of seminal fructose.Methods Totally 192 patients with low-quality sperm motility were randomized into treatment group of 97 cases and control group of 95 cases. The treatment group was given Supplemented Wuzi Yanzong Decoction one dose daily. The control group was given Liuwei Dihuang Pill 6g once

three times daily. One treatment course lasted for 3 months. The therapeutic effect

sperm motility and neutral α-glucosidase were observed.Results The total effective rate of the treatment group and control group was 81.44% and 57.89% respectively

with a significant difference between groups （P<0.01）. The sperm motility improved significantly in both groups after treatment （P<0.05 or P<0.01）

especially in the treatment group （P<0.05）. The content of seminal fructose and the level of α-glycosidase improved significantly after treatment in the treatment group （P<0.05）.Conclusion Supplemented Wuzi Yanzong Decoction can improve the sperm motility and increase the secretion of seminal fructose.

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