LI Ying 1, WANG Xuejing 1, ZHANG Shunan 1, et al. A Clinical Observation on Feiwei Granules for 61 Cases of Pulmonary Fibrosis[J]. Journal of Traditional Chinese Medicine2013, 54(6): 496-499.
LI Ying 1, WANG Xuejing 1, ZHANG Shunan 1, et al. A Clinical Observation on Feiwei Granules for 61 Cases of Pulmonary Fibrosis[J]. Journal of Traditional Chinese Medicine2013, 54(6): 496-499.DOI: 10.13288/j.11-2166/r.2013.06.015.
A Clinical Observation on Feiwei Granules for 61 Cases of Pulmonary Fibrosis
Objective To observe the therapeutic effect of Feiwei Granules (granules for lung wilting) for pulmonary fibro-sis.Methods Totally 120cases of pulmonary fibrosis were randomized into the treatment group and control group
with 61 and 59in each.Both groups were given the fundamental treatment.The treatment group was given 100ml Feiwei Granules twice daily.The control group was given 30 mg prednisone once daily.The treatment lasted for 2months.The Chinese medi-cine syndrome efficacy and patient satisfaction was evaluated.The Chinese medicine syndrome score
dyspnea score
quality of life score (Q OLS)
6-minute walk test
total lung capacity (T LC)
forced vital capacity (F VC)
forced expiratory volume in one second (F EV1)
F EV1/FVC and diffusing capacity of the lung for carbon monoxide (D LCO) were observed before and af-ter treatment.Results The Chinese medicine syndrome efficacy in the treatment group and control group was 62.3%and 32.2%respectively
with a significant difference between groups (P<0.01).The patient satisfaction rate in the treatment group and control group was 91.4%and 33.3%respectively
with a significant difference between groups (P<0.01).The Chinese medicine syndrome score
dyspnea score
Q OLS
6-minute walk test
TLC and FEV1were significantly improved in the treat-ment group after treatment (P<0.05or P<0.01).The Chinese medicine syndrome score
dyspnea score and QOLS were sig-nificantly improved in the control group after treatment (P<0.05or P<0.01)
but FVC was deteriorated after treatment (P<0.05).The treatment group was more effective in Chinese medicine syndrome score
Q OLS
6-minute walk test and FVC as compared with the control group (P<0.05or P<0.01).Conclusion Feiwei Granules is effective for pulmonary fibrosis in relieving Chinese medicine symptoms and dyspnea and improving QOL and lung function.