Literature Study on the Application of Orally Taken Chinese Medicinal for Knee Osteoarthritis

ZHANG Lei 1; LI Jubao1; ZENG Yan1; QU Shangke1; LI Xiaoyuan1; LHang1; CHEN Taibo1; LI Fanbing1; WANG Qi 1; BAO Ke1

doi:10.13288/j.11-2166/r.2013.07.017

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Literature Study on the Application of Orally Taken Chinese Medicinal for Knee Osteoarthritis

更新时间：2021-11-17

- Literature Study on the Application of Orally Taken Chinese Medicinal for Knee Osteoarthritis
- Journal of Traditional Chinese Medicine Vol. 54, Issue 7, Pages: 608-610(2013)
- 作者机构：
  
  1. 云南中医学院第一附属医院
  2. 云南省中医骨关节病诊疗中心
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2013.07.017
  CLC： R274
- Published：2013
- 稿件说明：
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[1]张磊,李具宝,曾炎,屈尚可,李晓媛,吕航,陈泰玻,李帆冰,王琦,包可.膝关节骨性关节炎内服中药使用情况文献分析[J].中医杂志,2013,54(07):608-610.

ZHANG Lei 1, LI Jubao1, ZENG Yan1, et al. Literature Study on the Application of Orally Taken Chinese Medicinal for Knee Osteoarthritis[J]. Journal of Traditional Chinese Medicine2013, 54(7): 608-610.
[1]张磊,李具宝,曾炎,屈尚可,李晓媛,吕航,陈泰玻,李帆冰,王琦,包可.膝关节骨性关节炎内服中药使用情况文献分析[J].中医杂志,2013,54(07):608-610. DOI： 10.13288/j.11-2166/r.2013.07.017.

ZHANG Lei 1, LI Jubao1, ZENG Yan1, et al. Literature Study on the Application of Orally Taken Chinese Medicinal for Knee Osteoarthritis[J]. Journal of Traditional Chinese Medicine2013, 54(7): 608-610. DOI： 10.13288/j.11-2166/r.2013.07.017.

摘要

目的通过近10年文献初步探讨膝关节骨性关节炎（KOA）内服中药的用药规律。方法检索2002至2012年收录于维普中文科技期刊数据库、中国期刊全文数据库、万方数据库的中药内服治疗KOA的临床文献

筛选符合标准的文献

采用频数统计的方法统计中药内服治疗KOA的总体用药频次、药对频次。结果纳入研究文献共491篇

包括572味中药、23个药对

药物总使用频次为5120次

使用频次最高的前10位依次为牛膝、当归、白芍、甘草、熟地黄、杜仲、川芎、独活、威灵仙、黄芪;药对总使用频次为891次

使用频次最高的前10位依次为牛膝和杜仲、黄芪和当归、桃仁和红花、独活和桑寄生、川乌和草乌、牛膝和当归、白芍和甘草、麻黄和桂枝、乳香和没药、黄柏和苍术。结论近10年治疗KOA内服方的药物组成以补肝脾肾、祛风寒湿为主;药对以补益肝肾、强筋壮骨以及益气活血为主。

Abstract

Objective To research the application laws of orally taken Chinese medicinal for knee osteoarthritis（KOA）according to the related literature in recent 10years.Methods The clinical literature on KOA treated with orally taken Chinese medicinal was searched in VIP Chinese Science and Technology Periodical Database

China Academic Journal and Wanfang Database from 2002to 2012.The standards-compliant articles were included and the total medication frequency and medicinal pair frequency were analyzed with frequency statistics.Results There were 491articles

572Chinese medicinals and 23medicinal pairs included.The total medication frequency was 5 120and the top 10medicinals were:Niuxi（Radix Achyranthis bidentatae）

Danggui（Radix Angelicae sinensis）

Baishao（Radix Paeoniae alba）

Gancao（Radix et Rhizoma Glycyrrhizae）

Shudihuang（Radix Rehmanniae praeparata）

Duzhong（Cortex Eucommiae）

Chuanxiong（Rhizoma Chuanxiong）

Duhuo（Radix Angelicae pubescentis）

Weilingxian（Radix et Rhizoma Clematidis）and Huangqi（Radix Astragali）.The medicinal pair frequency was 891and the top 10pairs were:Niuxi-Duzhong

Huangqi-Danggui

Taoren（Semen Persicae）-Honghua（Flos Carthami）

Duhuo-Sangjisheng（Herba Taxilli）

Chuanwu（Radix Aconiti）-Caowu（Radix Aconiti Kusnezoffii）

Niuxi-Danggui

Baishao-Gancao

Mahuang（Herba Ephedrae）-Guizhi（Ramulus Cinnamomi）

Ruxiang（Olibanum）-Moyao（Myrrha）and Huangbai（Cortex Phellodendri Chinensis）-Cangzhu（Rhizoma Atractylodis）.Conclusion The orally taken Chinese medicinal for KOA in recent 10years is mainly composed with liver-spleen-kidney-supplementing and wind-cold-dampdispelling medicinal and the role of medicinal pair is commonly supplementing the liver and kidney

strengthening sinew and bone

boosting qi and quickening the blood.

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