Clinical Observation on Psychosomatic Therapy for Depression in 27 Rheumatoid Arthritis Patients

WANG Jiandong1; YAN Xiaoping2

doi:10.13288/j.11-2166/r.2013.13.014

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Clinical Observation on Psychosomatic Therapy for Depression in 27 Rheumatoid Arthritis Patients

更新时间：2021-11-17

- Clinical Observation on Psychosomatic Therapy for Depression in 27 Rheumatoid Arthritis Patients
- Journal of Traditional Chinese Medicine Vol. 54, Issue 13, Pages: 1131-1134(2013)
- 作者机构：
  
  1. 中国中医科学院广安门医院
  2. 卫生部中日友好医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2013.13.014
  CLC： R259
- Published：2013
- 稿件说明：
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[1]王建东,阎小萍.心身同治法治疗类风湿关节炎伴发抑郁症27例临床观察[J].中医杂志,2013,54(13):1131-1134.

WANG Jiandong1, YAN Xiaoping2. Clinical Observation on Psychosomatic Therapy for Depression in 27 Rheumatoid Arthritis Patients[J]. Journal of Traditional Chinese Medicine2013, 54(13): 1131-1134.
[1]王建东,阎小萍.心身同治法治疗类风湿关节炎伴发抑郁症27例临床观察[J].中医杂志,2013,54(13):1131-1134. DOI： 10.13288/j.11-2166/r.2013.13.014.

WANG Jiandong1, YAN Xiaoping2. Clinical Observation on Psychosomatic Therapy for Depression in 27 Rheumatoid Arthritis Patients[J]. Journal of Traditional Chinese Medicine2013, 54(13): 1131-1134. DOI： 10.13288/j.11-2166/r.2013.13.014.

摘要

目的评价心身同治法治疗类风湿关节炎（RA）伴发抑郁症的临床疗效。方法将RA伴发抑郁症患者56例随机分为治疗组27例和对照组29例

治疗组采用补肾治尪汤配合燮枢解郁方及心理干预;对照组仅给予补肾治尪汤加减治疗

两组疗程均为4周。疗程结束后观察两组患者中医、西医及抑郁症疗效

并于治疗前后观察两组患者中医证候积分、抑郁自评量表积分（SDS）、疼痛VAS评分、总体情况VAS评分、晨僵时间、红细胞沉降率（ESR）、C反应蛋白（CRP）、类风湿因子（RF）。结果治疗组中医疗效、西医疗效、抑郁症疗效总有效率分别为88.88%、59.26%、85.19%

对照组分别为75.86%、48.28%、62.06%

治疗组中医疗效、抑郁症疗效均优于对照组（P<0.05）。治疗后两组ESR、CRP、RF均较治疗前明显改善（P<0.05或P<0.01）。治疗后治疗组中医证候积分、SDS积分、疼痛VAS评分、总体情况VAS评分及晨僵时间均较治疗前明显改善（P<0.05或P<0.01）;对照组中医证候积分、疼痛VAS评分、晨僵时间均较治疗前改善（P<0.05）。治疗后治疗组SDS积分、疼痛VAS积分和晨僵时间均较对照组明显改善（P<0.05）。结论补肾祛寒治尪汤配合燮枢解郁方及心理干预的心身同治法能够有效缓解RA患者伴发的抑郁症状及RA症状。

Abstract

Objective To evaluate the therapeutic effect of Bushen Quhan Zhiwang Decoction （Kidney-Supplementing Cold-Dispelling Lameness Decoction）

Xieshu Jieyu Formula （Pivot-Harmonizing Depression-Resolving Formula） and psychological intervention for depression in rheumatoid arthritis （RA） patients. Methods Totally 56 RA patients with depression were randomized into treatment group of 27 cases and control group of 29 cases. The treatment group was given Bushen Zhiwang Decoction

Xieshu Jieyu Formula and psychological intervention. The control group was given Bushen Zhiwang Decoction. The treatment lasted for 4 weeks. The TCM efficacy

western medicine efficacy and depression efficacy were observed after treatment. The TCM pattern score

self-rating depression scale （SDS） score

visual analog scale （VAS） pain score

VAS overall score

duration of morning stiffness （h）

erythrocyte sedimentation rate （ESR）

C-reactive protein （CRP） and rheumatoid factor （RF） were observed before and after treatment. Results The total effective rate of TCM

western medicine and depression in the treatment group was 88.88%

59.26% and 85.19% respectively. The total effective rate of TCM

western medicine and depression in the control group was 75.86%

48.28% and 62.06% respectively. The total effective rate of TCM and depression in the treatment group was superior to those in the control group （P<0.05）. The ESR

CRP and RF was significantly improved in both groups after treatment （P<0.05 or P<0.01）. The TCM pattern score

SDS score

VAS pain score

VAS overall score and duration of morning stiffness was significantly improved in the treatment group after treatment （P<0.05 or P<0.01）. The TCM pattern score

VAS pain score and duration of morning stiffness was significantly improved in the control group after treatment （P<0.05）. Comparing with the control group

the SDS score

VAS pain score and duration of morning stiffness was significantly improved in the treatment group after treatment （P<0.05）. Conclusion Bushen Zhiwang Decoction

Xieshu Jieyu Formula and psychological intervention can obviously relieve the symptoms of RA and depression.

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Related Institution

Beijing Hospital of Traditional Chinese Medicine，Capital Medical University

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The First Affiliated Hospital of Anhui University of Chinese Medicine/Anhui Provincial Key Laboratory for Applied Basic and Clinical Translational Research of Traditional Chinese Medicine Rheumatology

Affiliated Hospital of Jiangxi University of Chinese Medicine

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