Objective To observe the efficacy and influencing factors of electro-acupuncture（EA）combined with auricular acupuncture（AA）for type 2diabetes.Methods Totally 203cases of type 2diabetes were given combo therapy of EA and AA.The fasting blood sugar（FBS）

total cholesterol（TC）

triglyceride（TG）

high-density lipoprotein cholesterol（HDL-C）

low-density lipoprotein cholesterol（LDL-C）

fasting leptin（FLP）

fasting insulin（FINS）

insulin sensitivity index（ISI）and homeostasis model assessment for insulin resistance（HOMA-IR）andβ-cell function（HOMA-β）was observed before and after treatment.The relevant factors on the efficacy of EA such as patterns

obesity degree

age

duration

etiology and incentives were analyzed.Results After 3-month treatment

FBS

TC

TG

LDL

FINS

HOMA-IR and FLP significantly decreased（P<0.01）but HDL

ISI and HOMA-βsignificantly increased（P<0.01）in 203patients.Three patterns had no impact on the efficacy（P>0.05）.The obesity degree

age and duration affected the efficacy（P<0.01）.Conclusion EA combined with AA can obviously improve blood sugar

blood lipid andβ-cell function.It is effective for type 2diabetes patients with mild obesity

younger age and short duration.