Clinical Observation on Shenling Fuzheng Capsule Combined with HAART for 60 Cases of HIV/AIDS

LI Xuan; SU Qijian; LI Yizhong; LIU Zhenwei; WU Weiqun; LU Zhenzhen; DENG Xin

doi:10.13288/j.11-2166/r.2013.19.026

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Clinical Observation on Shenling Fuzheng Capsule Combined with HAART for 60 Cases of HIV/AIDS

更新时间：2021-11-17

- Clinical Observation on Shenling Fuzheng Capsule Combined with HAART for 60 Cases of HIV/AIDS
- Journal of Traditional Chinese Medicine Vol. 54, Issue 19, Pages: 1653-1656(2013)
- 作者机构：
  
  1. 广西中医药大学附属瑞康医院中医/中西医结合艾滋病研究中心
  2. 中南大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2013.19.026
  CLC： R512.91
- Published：2013
- 稿件说明：
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[1]李璇,苏齐鉴,李益忠,刘振威,吴卫群,陆珍珍,邓鑫.参灵扶正胶囊联合高效抗逆转录病毒疗法治疗艾滋病病毒感染者或艾滋病患者60例[J].中医杂志,2013,54(19):1653-1656.

LI Xuan, SU Qijian, LI Yizhong, et al. Clinical Observation on Shenling Fuzheng Capsule Combined with HAART for 60 Cases of HIV/AIDS[J]. Journal of Traditional Chinese Medicine2013, 54(19): 1653-1656.
[1]李璇,苏齐鉴,李益忠,刘振威,吴卫群,陆珍珍,邓鑫.参灵扶正胶囊联合高效抗逆转录病毒疗法治疗艾滋病病毒感染者或艾滋病患者60例[J].中医杂志,2013,54(19):1653-1656. DOI： 10.13288/j.11-2166/r.2013.19.026.

LI Xuan, SU Qijian, LI Yizhong, et al. Clinical Observation on Shenling Fuzheng Capsule Combined with HAART for 60 Cases of HIV/AIDS[J]. Journal of Traditional Chinese Medicine2013, 54(19): 1653-1656. DOI： 10.13288/j.11-2166/r.2013.19.026.

摘要

目的探讨参灵扶正胶囊联合高效抗逆转录病毒疗法（HAART）治疗艾滋病病毒（HIV）感染者或艾滋病（AIDS）患者的临床疗效。方法将60例HIV/AIDS患者随机分为治疗组和对照组各30例

治疗组给予参灵扶正胶囊及HAART

对照组给予HAART

两组均治疗6个月

观察两组临床疗效、常见毒副反应发生情况、生存质量积分及其他不良反应。结果治疗组有效30例

对照组有效29例

两组比较差异无统计学意义（P>0.05）。治疗组治疗后生存质量积分中生理领域、心理领域、独立性领域、总体健康状况和总体生存质量评分均较治疗前明显提高（P<0.05）;对照组治疗后独立性领域、总体健康状况和总体生存质量评分与治疗前比较明显提高（P<0.05）;治疗后生理领域、心理领域、总体健康状况和总体生存质量评分治疗组均高于对照组（P<0.05）。治疗后治疗组患者出现了恶心（或呕吐）、头痛、疲乏、眩晕、腹泻、腹胀、肝功能异常和骨髓抑制;对照组患者出现了恶心（或呕吐）、疲乏、眩晕、腹泻、腹胀、皮疹、肝功能异常和骨髓抑制

治疗组恶心（或呕吐）、疲乏发生率与对照组比较差异有统计学意义（P<0.05）。结论参灵扶正胶囊联合HAART治疗HIV/AIDS患者

能够提高患者生存质量

减少恶心（或呕吐）、疲乏等毒副反应的发生。

Abstract

Objective To research the therapeutic effect of Shenling Fuzheng Capsule[right-supporting capsule of Dangshen（Radix Codonopsis）and Lingzhi（Ganoderma）]combined with highly active antiretroviral therapy（HAART）on 60cases of human immunodeficiency virus infection/acquired immunodeficiency syndrome（HIV/AIDS）.Methods Sixty cases of HIV/ AIDS were randomized to the treatment group and control group

with 30in each.The treatment group was given Shenling Fuzheng Capsule and HAART.The control group was given HAART.The treatment lasted for 6months.The therapeutic effect

common adverse reactions

quality of life（QOL）and renal function were observed in both groups.Results There were 30and 29effective cases in the treatment group and control group respectively

with no significant difference between groups（P>0.05）.The scores of physiology

emotion

independence

overall health status and QOL were significantly improved in the treatment group after treatment（P<0.05）.The scores of independence

overall health status and QOL were significantly improved in the control group after treatment（P<0.05）.The scores of physiology

emotion

overall health status and QOL in the treatment group were significantly higher than those in the control group（P<0.05）.After treatment

patients in the treatment group experienced nausea（or vomiting）

fatigue

dizziness

diarrhea

abdominal distension

abnormal liver function or bone marrow suppression.The patients in the control group experienced nausea（or vomiting）

fatigue

dizziness

rash

abnormal liver function or bone marrow suppression.There were significant differences between groups in nausea（or vomiting） and fatigue（P<0.05）

but with no significant difference between groups in other symptoms（P>0.05）.Conclusion Shenling Fuzheng Capsule combined with HAART can improve QOL and reduce the incidence of nausea（or vomiting）and fatigue in HIV/AIDS patients.

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