A Clinical Observation on Xiaoer Kechuanning Oral Liquid Combined with Western Medicine for 34 Cases of Bronchiolitis at Acute Stage

HUANG Teng; ZHOU Jiewen; Xu Youjia

doi:10.13288/j.11-2166/r.2013.20.012

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A Clinical Observation on Xiaoer Kechuanning Oral Liquid Combined with Western Medicine for 34 Cases of Bronchiolitis at Acute Stage

更新时间：2021-11-17

- A Clinical Observation on Xiaoer Kechuanning Oral Liquid Combined with Western Medicine for 34 Cases of Bronchiolitis at Acute Stage
- Journal of Traditional Chinese Medicine Vol. 54, Issue 20, Pages: 1747-1750(2013)
- 作者机构：
  
  广东省中医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2013.20.012
  CLC： R272
- Published：2013
- 稿件说明：
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[1]黄腾,周洁雯,许尤佳.小儿咳喘宁口服液联合西药治疗毛细支气管炎急性期34例临床观察[J].中医杂志,2013,54(20):1747-1750.

HUANG Teng, ZHOU Jiewen, Xu Youjia. A Clinical Observation on Xiaoer Kechuanning Oral Liquid Combined with Western Medicine for 34 Cases of Bronchiolitis at Acute Stage[J]. Journal of Traditional Chinese Medicine2013, 54(20): 1747-1750.
[1]黄腾,周洁雯,许尤佳.小儿咳喘宁口服液联合西药治疗毛细支气管炎急性期34例临床观察[J].中医杂志,2013,54(20):1747-1750. DOI： 10.13288/j.11-2166/r.2013.20.012.

HUANG Teng, ZHOU Jiewen, Xu Youjia. A Clinical Observation on Xiaoer Kechuanning Oral Liquid Combined with Western Medicine for 34 Cases of Bronchiolitis at Acute Stage[J]. Journal of Traditional Chinese Medicine2013, 54(20): 1747-1750. DOI： 10.13288/j.11-2166/r.2013.20.012.

摘要

目的评价小儿咳喘宁口服液治疗呼吸道合胞病毒（RSV）感染毛细支气管炎急性期的临床疗效。方法 68例RSV毛细支气管炎急性期患儿随机分为治疗组与对照组各34例

两组均采用西医常规对症治疗

治疗组加服小儿咳喘宁口服液

疗程7天。对患儿咳嗽、喘憋、喉中痰鸣、肺部啰音症状、体征进行评分

并观察Bierman病情评分的改善情况。于治疗前后进行尿白三烯E4（LTE4）测定。结果治疗组临床疗效总有效率（97.05%）优于对照组（88.24%）（P<0.05）。治疗组在改善咳嗽、喉中痰鸣、肺部啰音等症状、体征及缩短住院天数方面均优于对照组（P<0.01）。治疗后3天治疗组喘憋评分及Bierman评分明显低于对照组（P<0.05）。两组患儿尿LTE4治疗前后比较差异均有统计学意义（P<0.05）

但两组治疗后7天组间比较差异无统计学意义（P>0.05）。结论小儿咳喘宁口服液可改善RSV感染毛细支气管炎急性期患儿咳嗽、喘憋、喉中痰鸣及肺部啰音等症状体征

缩短住院天数

提高临床疗效。

Abstract

Objective To study the therapeutic effect and mechanism of Xiaoer Kechuanning Oral Liquid（oral liquid for pediatric cough and asthma）for respiratory syncytial virus（RSV）infection and bronchiolitis.Methods Totally 68children with RSV infection and bronchiolitis were randomized into the treatment group and control group.Both groups were given routine western medicine.The treatment group was added with Xiaoer Kechuanning Oral Liquid.The treatment lasted for 7 days.The improvement of coughing

wheezing

throat phlegm

pulmonary rales and Bierman’s score was observed.The level of urinary leukotriene E4（LTE4）was detected before and after treatment.Results The total effective rate of the treatment group and control group was 97.05%and 88.24%respectively

with a significant difference between groups（P<0.05）.The treatment group was superior to the control group in relieving coughing

throat phlegm and pulmonary rales and shortening hospital stay（P<0.01）.On the 3rd day after treatment

the wheezing score and Bierman’s score in the treatment group were significantly lower than that in the control group（P<0.05）.The levels of LTE4were significantly decreased in both groups after treatment（P<0.05）

but with no significant difference between groups on the 7th day after treatment（P>0.05）.Conclusion Xiaoer Kechuanning Oral Liquid is effective for RSV infection and bronchiolitis in children and it can relieve coughing

wheezing

throat phlegm and pulmonary rales

shorten hospital stay and increase clinical efficacy.

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Related Institution

The First Clinical College of Liaoning University of Traditional Chinese Medicine

The First Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

Doctorate Student,The First College of Clinical Medicine,Nanjing University of Chinese Medicine

Postgraduate of Nanjing University of Chinese Medicine

Medicine and Life Sciences College,Nanjing University of Chinese Medicine

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