Thinking of Chinese Medicine Treatment of Parkinson’s Disease Based on Neurovascular Unit

LI Min; YANG Minghui; LIU Yi

doi:10.13288/j.11-2166/r.2014.01.005

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Thinking of Chinese Medicine Treatment of Parkinson’s Disease Based on Neurovascular Unit

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- Thinking of Chinese Medicine Treatment of Parkinson’s Disease Based on Neurovascular Unit
- Journal of Traditional Chinese Medicine Vol. 55, Issue 1, Pages: 19-21(2014)
- 作者机构：
  
  中国人民解放军总医院中医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2014.01.005
  CLC： R277.7
- Published：2014
- 稿件说明：
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[1]李敏,杨明会,刘毅.从神经血管单元探讨中医药治疗帕金森病的思路[J].中医杂志,2014,55(01):19-21.

LI Min, YANG Minghui, LIU Yi. Thinking of Chinese Medicine Treatment of Parkinson’s Disease Based on Neurovascular Unit[J]. Journal of Traditional Chinese Medicine2014, 55(1): 19-21.
[1]李敏,杨明会,刘毅.从神经血管单元探讨中医药治疗帕金森病的思路[J].中医杂志,2014,55(01):19-21. DOI： 10.13288/j.11-2166/r.2014.01.005.

LI Min, YANG Minghui, LIU Yi. Thinking of Chinese Medicine Treatment of Parkinson’s Disease Based on Neurovascular Unit[J]. Journal of Traditional Chinese Medicine2014, 55(1): 19-21. DOI： 10.13288/j.11-2166/r.2014.01.005.

摘要

帕金森病（PD）临床治疗主要以多巴胺（DA）替代疗法为主

疗效并不理想。近年来研究表明

神经血管单元包括脑血管内皮转运机制异常所导致的神经毒性物质清除障碍以及与DA能神经元、胶质细胞相互作用功能异常可能是PD发病的重要原因。重视神经血管单元中各成分的相互作用

将其作为一个功能性整体来研究

并运用中药多组分、多层次、多靶点和多机制的优势

在诸多靶点中选择有效的干预

是中医药治疗PD的新思路。

Abstract

The common replacement therapy of Parkinson’s disease（ PD）

dopamine（ DA） is of less satisfac- tion. Recent studies have shown that brain microvascular endothelial cells（ BMEC） and non-neuronal cells in the nervous system played an important role in the development and progression of PD. Chinese medicinal has multi- component

multi-level

multi-target and multi-mechanism advantage. A new idea of Chinese medicine for PD is discussed based on recent research progress in neurovascular unit（ NVU）

the advantage of Chinese medicinal and other concepts.

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Related Institution

广州中医药大学第二临床医学院，广东省广州市番禺区大学城外环东路232号

广州中医药大学第二附属医院

Nanjing Hospital of Traditional Chinese Medicine Affiliated to Nanjing University of Chinese Medicine

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