Objective To observe the real-world clinical applications and safety of Xiyanping Injection（喜炎平注 射液）. Methods Patients injected with Xiyanping Injection（喜炎平注射液） were observed from September 2012 to October 2013 with a prospective

multi-center

large sample and centralized monitoring method. The overall condition of patients

diagnosis

treatment and adverse reactions（ADR） were analyzed. Results Most patients injected with Xiyanping Injection（ 喜炎平注射液） were children. The treatment course was mostly within five days. The indications were pneumonia

bronchitis

lung infections and respiratory tract infections. The common TCM patterns were syndrome of wind-heat invading the lung and pattern of phlegm-heat brewing in the lung. ARD occurred in 7 patients（0. 17%）. The occurrence of ADR was related to the manufacturer

lot number

drip rate

other injections and nonstandard operations. Conclusion Xiyanping Injection（ 喜炎平注 射液） is commonly used to treat respiratory diseases with syndrome of wind-heat invading the lung or syndrome of phlegm-heat brewing in the lung. ADR is occasionally occurred in the elderly or children suffering from infectious diseases.