Correlation of Patterns,Large Vessel Disease and Small Vessel Disease in Acute Ischemic Stroke

ZHANG Na; CHEN Zhigang; CAI Yingli; GAO Fang; LIU Qiang

doi:10.13288/j.11-2166/r.2014.08.013

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Correlation of Patterns,Large Vessel Disease and Small Vessel Disease in Acute Ischemic Stroke

更新时间：2021-11-17

- Correlation of Patterns,Large Vessel Disease and Small Vessel Disease in Acute Ischemic Stroke
- Journal of Traditional Chinese Medicine Vol. 55, Issue 8, Pages: 673-676(2014)
- 作者机构：
  
  1. 北京中医药大学东方医院
  2. 世界中医药学会联合会
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2014.08.013
  CLC： R255.2
- Published：2014
- 稿件说明：
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[1]张娜,陈志刚,蔡英丽,高芳,刘强.缺血性中风急性期证候与大小动脉病变的相关性[J].中医杂志,2014,55(08):673-676.

ZHANG Na, CHEN Zhigang, CAI Yingli, et al. Correlation of Patterns,Large Vessel Disease and Small Vessel Disease in Acute Ischemic Stroke[J]. Journal of Traditional Chinese Medicine2014, 55(8): 673-676.
[1]张娜,陈志刚,蔡英丽,高芳,刘强.缺血性中风急性期证候与大小动脉病变的相关性[J].中医杂志,2014,55(08):673-676. DOI： 10.13288/j.11-2166/r.2014.08.013.

ZHANG Na, CHEN Zhigang, CAI Yingli, et al. Correlation of Patterns,Large Vessel Disease and Small Vessel Disease in Acute Ischemic Stroke[J]. Journal of Traditional Chinese Medicine2014, 55(8): 673-676. DOI： 10.13288/j.11-2166/r.2014.08.013.

摘要

目的探讨缺血性中风急性期证候与大动脉病变（LVD）、小动脉病变（SVD）的相关性。方法将207例缺血性中风急性期患者分为LVD组87例、SVD组120例

比较两组患者的中医证候、病史、并发症、血常规、颅内外血管超声学检查、美国国立卫生研究院卒中量表（NIHSS）、改良Rankin量表（MRS）及日常生活活动能力量表（ADL）评分

并采用logistic回归对相关因素进一步分析。结果两组患者痰证单项条目评分、阴虚阳亢证发生率、房颤、冠心病、心脏病史、心律失常并发症、淋巴细胞百分比（LYM%）、高密度脂蛋白（HDL）、低密度脂蛋白（LDL）、TCD血管高流速、NIHSS、MRS量表评分差异有统计学意义（P<0.05）

并采用logistic回归对上述因素进一步分析得出

冠心病史、LDL、TCD血管高流速、MRS量表评分与LVD相关（P<0.05）

LDL与SVD相关（P<0.05）。结论缺血性中风急性期大小动脉病变表现出不同的证候特征。

Abstract

Objective To study the correlation of patterns

indicators

large vessel disease（ LVD） and small vessel disease（ SVD） in acute ischemic stroke. Methods Totally 207 cases of acute ischemic stroke were divided into the LVD group and SVD group

with 87 and 120 in each. The patterns

medical history

complications

routine blood test

ultrasound examination of intracranial vascular and scores of National Institutes of Health Stroke Scale（ NIHSS）

modified Rankin Scale（ MRS） and activities of daily living（ ADL） scale were compared in both groups. The related factors were analyzed with logistic regression. Results There were significant differences between groups in the score of phlegm pattern

incidence of yin deficiency yang hyperactivity pattern

atrial fibrillation

coronary heart disease（ CHD）

history of heart disease

arrhythmia

lymphocyte ratio（ LYM%）

high-density lipoprotein cholesterol（ HDL-C）

low-density lipoprotein cholesterol（ LDL-C）

high Transcranial Doppler（ TCD） blood flow velocity

NIHSS score and MRS score（ P < 0. 05）. CHD history

LDL

high TCD blood flow velocity and MRS score were related to LVD（ P < 0. 05）. LDL was related to SVD（ P < 0. 05）. Conclusion LVD and SVD of acute ischemic stroke show different patterns.

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