Clinical Observation on Modified Maxing Shigan Decoction According to Symptoms for 18 Children With Bronchial Pneumonia

DU Hongzhe; JIN Li; CHEN Hanjiang; HAN Yaowei

doi:10.13288/j.11-2166/r.2014.10.010

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Clinical Observation on Modified Maxing Shigan Decoction According to Symptoms for 18 Children With Bronchial Pneumonia

更新时间：2021-11-17

- Clinical Observation on Modified Maxing Shigan Decoction According to Symptoms for 18 Children With Bronchial Pneumonia
- Journal of Traditional Chinese Medicine Vol. 55, Issue 10, Pages: 842-845(2014)
- 作者机构：
  
  1. 天津中医药大学第一附属医院
  2. 天津中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2014.10.010
  CLC： R272
- Published：2014
- 稿件说明：
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[1]杜洪喆,晋黎,陈汉江,韩耀巍.麻杏石甘汤随症施量模式治疗小儿支气管肺炎18例临床研究[J].中医杂志,2014,55(10):842-845.

DU Hongzhe, JIN Li, CHEN Hanjiang, et al. Clinical Observation on Modified Maxing Shigan Decoction According to Symptoms for 18 Children With Bronchial Pneumonia[J]. Journal of Traditional Chinese Medicine2014, 55(10): 842-845.
[1]杜洪喆,晋黎,陈汉江,韩耀巍.麻杏石甘汤随症施量模式治疗小儿支气管肺炎18例临床研究[J].中医杂志,2014,55(10):842-845. DOI： 10.13288/j.11-2166/r.2014.10.010.

DU Hongzhe, JIN Li, CHEN Hanjiang, et al. Clinical Observation on Modified Maxing Shigan Decoction According to Symptoms for 18 Children With Bronchial Pneumonia[J]. Journal of Traditional Chinese Medicine2014, 55(10): 842-845. DOI： 10.13288/j.11-2166/r.2014.10.010.

摘要

目的观察麻杏石甘汤随症施量策略治疗小儿支气管肺炎（风热闭肺）的疗效。方法将37例支气管肺炎患儿随机分为随症施量组18例和不随症施量组19例。两组均给予西医基础用药

不随症施量组在基础用药同时给予麻杏石甘汤

每日1剂

分早、中、晚3次服用

每两次间隔不少于4h;随症施量组在基础用药同时根据体温分别给予不随症施量组每日量的1、1.5、2、2.5、3倍的麻杏石甘汤。记录两组患儿完全退热时间、痊愈时间、中医单项症状（咳嗽、痰鸣、喘促）的消失率及消失时间、不良反应发生率。治疗后评价两组临床疗效和中医证候疗效。结果随症施量组临床疗效总有效率为100%

高于不随症施量组的94.73%

但差异无统计学意义（P>0.05）。随症施量组中医证候疗效愈显率为88.89%

明显高于不随症施量组的15.79%（P<0.01）。随症施量组完全退热时间和咳嗽、痰鸣消失时间明显短于不随症施量组（P<0.05）;随症施量组咳嗽、痰鸣消失率明显高于不随症施量组（P<0.01）。两组均未出现不良反应。结论采用以发热为主要指征

以热退为标志

以倍增药物剂量为调整方式的随症施量策略的麻杏石甘汤治疗小儿支气管肺炎疗效优于非随症施量策略

能缩短发热、咳嗽、痰鸣时间。

Abstract

Objective To compare the efficacy of modified Maxing Shigan Decoction according to symptoms for children with bronchial pneumonia.Methods Totally 37 children with bronchial pneumonia were randomized into the modified dosage（ dosage modified according to symptoms） group and fixed dosage（ dosage not modified according to symptoms） group

with 18 and 19 in each.Both groups were given basic western medication.The fixed dosage group was added with Maxing Shigan Decoction one dose daily.Based on the body temperature of patients

the modified dosage group was added with 1

1.5

2.5 or 3 times daily volume of Maxing Shigan Decoction as in the fixed dosage group.The complete cooling time

recovery time

recovery rate and recovery time of TCM individual symptom

and incidence of adverse reactions were recorded.The clinical efficacy and TCM syndrome efficacy were evaluated after treatment.Results The total effective rate of the modified dosage group and fixed dosage group was 100% and 94.73% respectively

with no significant difference between groups（ P > 0.05）.The total effective rate of TCM syndromes in the modified dosage group and fixed dosage group was 88.89% and 15.79% respectively

with a significant difference between groups（ P < 0.01）.The complete cooling time

cough time and expectoration time in the modified dosage group was significantly shorter than those in the fixed dosage group（ P < 0.05）.The recovery rates of cough and expectoration in the modified dosage group were significantly higher than those in the fixed dosage group（ P < 0.05）.There was no adverse reaction in both groups.Conclusion Maxing Shigan Decoction is effective for bronchial pneumonia in children

especially modifying dosage according to symptoms with a shorter duration of fever

cough and expectoration.

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