Objective To observe the efficacy of Xiaoyin Jiedu Granules for psoriasis vulgaris and its effect on quality of life（ QOL）.Methods Eighty psoriasis vulgaris patients with blood heat syndrome were randomized into the treatment group and control group

with 40 in each.The patients in the treatment group were orally taken Xiaoyin Jiedu Granules one dose daily.The patients in the control group were orally taken Xiaoyin Granules 3.5 g each time and three times daily.The efficacy was evaluated after 8-week treatment in both groups.The itching degree

Body Surface Area（ BSA）

Psoriasis Area and Severity Index（ PASI）

Dermatology Life Quality Index（ DLQI） were scored before and after treatment.Results The total efficacy of the treatment group and control group was 85.00% and 82.05%

with no significant difference between groups（ P > 0.05）.The scores of PASI

itching degree

BSA and DLQI were significantly decreased in both groups after treatment（ P < 0.01）

especially DLQI in the treatment group（ P < 0.05）.There was no adverse reaction in both groups.Conclusion Xiaoyin Jiedu Granules is effective and safe for psoriasis vulgaris with blood heat syndrome

and it can obviously reduce the severity of psoriatic lesions and improve QOL.