Clinical Observation on Penqiangyan Granules（盆腔炎颗粒） for 145 Infertile Patients Caused by Pelvic Inflammation

YIN Yanyun; ZHOU Chunxiang; TAN Yong; CHEN Jie; BIAN Yaoyao

doi:10.13288/j.11-2166/r.2014.13.011

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Clinical Observation on Penqiangyan Granules（盆腔炎颗粒） for 145 Infertile Patients Caused by Pelvic Inflammation

更新时间：2021-11-17

- Clinical Observation on Penqiangyan Granules（盆腔炎颗粒） for 145 Infertile Patients Caused by Pelvic Inflammation
- Journal of Traditional Chinese Medicine Vol. 55, Issue 13, Pages: 1117-1119(2014)
- 作者机构：
  
  1. 南京中医药大学附属医院
  2. 南京中医药大学
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2014.13.011
  CLC： R271.14
- Published：2014
- 稿件说明：
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[1]殷燕云,周春祥,谈勇,陈婕,卞尧尧.盆腔炎颗粒治疗盆腔炎后遗症性不孕患者145例临床观察[J].中医杂志,2014,55(13):1117-1119.

YIN Yanyun, ZHOU Chunxiang, TAN Yong, et al. Clinical Observation on Penqiangyan Granules（盆腔炎颗粒） for 145 Infertile Patients Caused by Pelvic Inflammation[J]. Journal of Traditional Chinese Medicine2014, 55(13): 1117-1119.
[1]殷燕云,周春祥,谈勇,陈婕,卞尧尧.盆腔炎颗粒治疗盆腔炎后遗症性不孕患者145例临床观察[J].中医杂志,2014,55(13):1117-1119. DOI： 10.13288/j.11-2166/r.2014.13.011.

YIN Yanyun, ZHOU Chunxiang, TAN Yong, et al. Clinical Observation on Penqiangyan Granules（盆腔炎颗粒） for 145 Infertile Patients Caused by Pelvic Inflammation[J]. Journal of Traditional Chinese Medicine2014, 55(13): 1117-1119. DOI： 10.13288/j.11-2166/r.2014.13.011.

摘要

目的观察盆腔炎颗粒治疗盆腔炎后遗症不孕患者的临床疗效及安全性。方法将285例盆腔炎后遗症性不孕患者随机分为治疗组145例和对照组140例。对照组予常规口服抗生素方案:左氧氟沙星片每次500mg

每日1次;甲硝唑片每次400mg

每日3次。治疗组给予盆腔炎颗粒

每日1剂。两组均以14天为1个疗程

于月经结束后接受治疗

每个月经周期予以1个疗程

治疗3个疗程

若获得妊娠

继续随访。治疗结束继续观察6个月经周期后评价临床疗效和生育力（包括生化妊娠率、异位妊娠率、临床妊娠率、自然流产率、活产率等）

治疗过程中观察药物不良反应

治疗前后运用视觉模拟法（VAS）进行疼痛评分。结果治疗组临床疗效总有效率为95.2%

对照组为92.1%

两组比较差异无统计学意义（P>0.05）。两组患者治疗后VAS评分均明显降低（P<0.01）

两组患者治疗后VAS评分组间比较

差异无统计学意义（P>0.05）。治疗组患者治疗后临床妊娠率明显高于对照组（P<0.05）。治疗组消化系统和总的不良反应发生率明显低于对照组（P<0.05）。结论盆腔炎颗粒能提高盆腔炎后遗症性不孕患者临床妊娠率

安全性好。

Abstract

Objective To observe the therapeutic effect and safety of Penqiangyan Granules（granules to treat pelvic inflammation

盆腔炎颗粒）for infertility due to pelvic inflammation. Methods Totally 285cases of infertility due to pelvic inflammation were randomized into the treatment group of 145cases and control group of 140cases.The control group was treated with oral antibiotics.The treatment group was given Penqiangyan Granules one dose daily.One treatment course lasted for 14days.The patients were received treatment after menstruation clean.The patients were received one treatment course during each menstrual cycle for a total of three courses

and were followed up after pregnancy.After treatment

the patients were observed for 6menstrual cycles and the efficacy and fertility were evaluated.The adverse reactions were observed

and the pain was scored by visual analog scale（VAS）before and after treatment. Results The total effective rate of the treatment group and control group was 95.2%and 92.1%respectively

with no significant difference between groups（P>0.05）.The VAS scores were significantly decreased in both groups after treatment（P<0.01）

with no significant difference between groups（P>0.05）.The clinical pregnancy rate in the treatment group was significantly higher than that in the control group（P<0.05）.The incidence of adverse reactions in the treatment group was significantly lower than that in the control group（P<0.05）.Conclusion Penqiangyan Granules is effective and safe for infertility due to pelvic inflammation.It can improve the clinical pregnancy rate.

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