Objective To observe the efficacy and safety of Suanzaoren Longmu Decoction [decoction of Suanzaoren（ Semen Ziziphi Spinosae

酸枣仁）

Longgu（ Os Draconis

龙骨） and Muli（ Concha Ostreae

牡蛎） ]for insomnia patients with yin-deficiency

qi-stagnation and internal heat harassing the heart syndrome. Methods Sixty cases of insomnia were randomized into the treatment group and control group

with 30 in each. The treatment group was given Suanzaoren Longmu Decoction one dose daily. The control group was given 1 mg of Estazolam Tablets half an hour before bedtime. The efficacy was evaluated after 2-week treatment. The sleep efficiency

Pittsburgh Sleep Quality Index（ PSQI） and Self-Rating Scale of Sleep（ SRSS） were observed before and after treatment. Results The total effective rate of treatment group and control group was 90. 0% and 73. 33% respectively

with a significant difference between groups（ P < 0. 05）. The scores of PSQI and SRSS were significantly decreased in both groups after treatment

especially in the treatment group（ P < 0. 05）. The sleep efficacy was significantly increased in both groups after treatment

especially in the treatment group（ P < 0. 05）. Conclusion Suanzaoren Longmu Decoction can improve sleep quality and daytime functional status of insomnia patients

with a good safety.