Correlation Between TCM Syndromes and Serum High Sensitivity C-Reactive Protein and Superoxide Dismutase of Coronary Heart Disease Patients

LUO Min; HUANG Li; ZHANG Peiran; WANG Weigang; WANG Xian

doi:10.13288/j.11-2166/r.2014.22.011

您当前的位置：

首页 >

文章列表页 >

Correlation Between TCM Syndromes and Serum High Sensitivity C-Reactive Protein and Superoxide Dismutase of Coronary Heart Disease Patients

更新时间：2021-11-17

- Correlation Between TCM Syndromes and Serum High Sensitivity C-Reactive Protein and Superoxide Dismutase of Coronary Heart Disease Patients
- Journal of Traditional Chinese Medicine Vol. 55, Issue 22, Pages: 1926-1928(2014)
- 作者机构：
  
  1. 中日友好医院
  2. 北京中医药大学东直门医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2014.22.011
  CLC： R259
- Published：2014
- 稿件说明：
移动端阅览
[1]罗敏,黄力,张沛然,王伟钢,王显.冠心病患者血清超敏C反应蛋白及超氧化物歧化酶与中医证型的相关性[J].中医杂志,2014,55(22):1926-1928.

LUO Min, HUANG Li, ZHANG Peiran, et al. Correlation Between TCM Syndromes and Serum High Sensitivity C-Reactive Protein and Superoxide Dismutase of Coronary Heart Disease Patients[J]. Journal of Traditional Chinese Medicine2014, 55(22): 1926-1928.
[1]罗敏,黄力,张沛然,王伟钢,王显.冠心病患者血清超敏C反应蛋白及超氧化物歧化酶与中医证型的相关性[J].中医杂志,2014,55(22):1926-1928. DOI： 10.13288/j.11-2166/r.2014.22.011.

LUO Min, HUANG Li, ZHANG Peiran, et al. Correlation Between TCM Syndromes and Serum High Sensitivity C-Reactive Protein and Superoxide Dismutase of Coronary Heart Disease Patients[J]. Journal of Traditional Chinese Medicine2014, 55(22): 1926-1928. DOI： 10.13288/j.11-2166/r.2014.22.011.

摘要

目的探讨冠心病患者抗氧化标志物水平及其与中医证候分型的相关性。方法选择60名稳定型心绞痛（SAP）患者为SAP组

60名急性冠脉综合征（ACS）患者为ACS组

两组患者中医辨证分为心脉瘀阻证、痰浊内阻证、寒凝心脉证、心肾阴虚证、心肾阳虚证5型。另选60名健康体检者作为对照组

检测各组受试者血清超敏C反应蛋白（hs-CRP）和超氧化物歧化酶（SOD）水平

同时对不同中医证型的SAP、ACS患者hs-CRP、SOD水平进行相关性分析。结果 SAP组、ACS组的SOD水平较对照组明显下降

而hs-CRP水平较对照组明显升高

hs-CRP水平ACS组明显高于SAP组（P<0.05）。SAP组患者心肾阴虚证及心肾阳虚证患者hs-CRP水平明显低于心血瘀阻证（P<0.05）

各证型与hs-CRP具有相关性

相关系数r=-0.825（P<0.01）。ACS组患者各证型与hs-CRP具有相关性

相关系数r=-0.436（P<0.01）。结论冠心病患者血清hs-CRP水平与中医证型有一定相关性

炎症反应可能影响中医证型的形成。

Abstract

Objective To explore the antioxidant marker level of coronary heart disease（ CHD） patient and its correlation with traditional Chinese medicine（ TCM） syndromes. Methods Sixty stable angina pectoris（ SAP） patients were selected as SAP group and 60 acute coronary syndrome（ ACS） patients were selected as ACS group. The TCM syndromes of patients in both groups were obstruction of heart meridian

phlegm obstruction

coldness blocking heart meridian

heart-kidney yin-deficiency

and heart-kidney yang-deficiency. In addition

60 healthy people were selected as the control group. The levels of high sensitivity C-reactive protein（ hs-CRP） and superoxide dismutase（ SOD）of participants were detected in each group. At the same time

a correlation analysis on hs-CRP and SOD of SAP and ACS patients with different TCM syndromes was performed. Results Comparing with the control group

the level of SOD was significantly decreased but the level of hs-CRP was significantly increased in SAP group and ACS group

especially the level of hs-CRP in ACS group（ P < 0. 05）. In SAP group

the level of hs-CRP in patients with heartkidney yin-deficiency syndrome and heart-kidney yang-deficiency syndrome was significantly lower than that in patients with obstruction of heart meridian syndrome（ P < 0. 05）. Each TCM syndrome in SAP group had correlation with hs-CRP

and the correlation coefficient was- 0. 825（ P < 0. 01）. Each TCM syndrome in ACS group also had correlation with hs-CRP and the correlation coefficient was- 0. 436（ P < 0. 01）. Conclusion Serum hs-CRP level of CHD patients has a certain correlation with TCM syndrome

and inflammatory reaction may affect the formation of TCM syndrome.

关键词

Keywords

references

查看原文

Views

303

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Analysis of Clinical and Phenomics Characteristics of Patients with Phlegm-Stasis Binding Syndrome and Its Accompanied Patterns in Stable Angina Pectoris of Coronary Heart Disease

Pathogenesis Evolution and Staged Differentiation and Treatment Strategy of Atherosclerotic Plaques：from the Perspective of "Constraint-Putrefaction-Ulceration"

Effects of Yangxin Tongmai Formula （养心通脉方） on Methylation Key Genes and the PERK/ATF4/CHOP Signaling Pathway in Myocardial Tissue of Coronary Heart Disease Model Rats with Blood Stasis Syndrome

Qingxin Jieyu Granule （清心解瘀颗粒） for the Treatment of Acute Coronary Syndrome with Binding of Stasis and Toxin Syndrome：A Multicenter，Double-Blind，Placebo Randomize-Controlled Trial

Construction of a Diagnostic Model for Coronary Heart Disease with Blood Stasis Syndrome Based on Objective Multi-Modal Data Fusion

Related Author

LI Chongchai

LI Han

LI Zheng

LI Zeng

ZHOU Yushi

AO Yuhan

XU Shuang

WANG Xue

Related Institution

Liaoning University of Traditional Chinese Medicine

Shenyang Health Service Center

Affiliated Hospital of Liaoning University of Traditional Chinese Medicine

Clinical Evaluation Center，China Academy of Chinese Medical Sciences

Dongfang Hospital，Beijing University of Chinese Medicine

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰