Study on the Common Features in Damp-Heat Syndrome of Rheumatic Diseases Based on Trace Element Profiling

ZHAO Tie; ZHANG Yingze; WANG Xiaoxue; LU Jin; WANG Guochun; LI Ping; ZU Ning; YAN Xiaoping; ZHANG Xianglin

doi:10.13288/j.11-2166/r.2014.24.009

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Study on the Common Features in Damp-Heat Syndrome of Rheumatic Diseases Based on Trace Element Profiling

更新时间：2021-11-17

- Study on the Common Features in Damp-Heat Syndrome of Rheumatic Diseases Based on Trace Element Profiling
- Journal of Traditional Chinese Medicine Vol. 55, Issue 24, Pages: 2100-2105(2014)
- 作者机构：
  
  中日友好医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2014.24.009
  CLC： R259
- Published：2014
- 稿件说明：
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[1]赵铁,张英泽,王晓雪,陆进,王国春,李平,祖宁,阎小萍,张相林.基于微量元素组学的风湿性疾病湿热证共性特征研究[J].中医杂志,2014,55(24):2100-2105.

ZHAO Tie, ZHANG Yingze, WANG Xiaoxue, et al. Study on the Common Features in Damp-Heat Syndrome of Rheumatic Diseases Based on Trace Element Profiling[J]. Journal of Traditional Chinese Medicine2014, 55(24): 2100-2105.
[1]赵铁,张英泽,王晓雪,陆进,王国春,李平,祖宁,阎小萍,张相林.基于微量元素组学的风湿性疾病湿热证共性特征研究[J].中医杂志,2014,55(24):2100-2105. DOI： 10.13288/j.11-2166/r.2014.24.009.

ZHAO Tie, ZHANG Yingze, WANG Xiaoxue, et al. Study on the Common Features in Damp-Heat Syndrome of Rheumatic Diseases Based on Trace Element Profiling[J]. Journal of Traditional Chinese Medicine2014, 55(24): 2100-2105. DOI： 10.13288/j.11-2166/r.2014.24.009.

摘要

目的探讨风湿性疾病湿热证的共性特征。方法采用电感耦合等离子体质谱技术

对强直性脊柱炎（AS）湿热证患者、痛风性关节炎（GA）湿热证患者及健康志愿者的血清样本进行微量元素组学研究

比较AS湿热证患者、GA湿热证患者相对于健康志愿者血清中与湿热证相关的共性差异微量元素。结果模式识别分析显示

AS湿热证组与GA湿热证组分别与其对照组之间均表现出明显的分离趋势。与健康对照组比较

GA湿热证组和AS湿热证组均表现为血清铜、铷和铯水平的显著升高（P<0.01）。结论血清铜、铷和铯水平升高可能为风湿性疾病湿热证的共性元素特征。

Abstract

Objective To explore the common features of rheumatic diseases with damp-heat syndrome.Methods Inductively coupled plasma mass spectrometry（ ICP-MS） was applied to determinate trace element profiles of blood samples from ankylosing spondylitis（ AS） patients with damp-heat syndrome

gouty arthritis（ GA） patients with damp-heat syndrome

and healthy volunteers. Then the trace element profiles of different patients and healthy subjects were compared

and the common features in the trace element profiles of AS patients and GA patients which were different from those of healthy volunteers were investigated. Results Compared with healthy control group

both GA damp-heat group and AS damp-heat group showed significant increase levels of copper

rubidium and cesium in blood serum. Conclusion The increased serum levels of copper

rubidium and cesium may be the common elementary features in damp-heat syndrome of rheumatic diseases.

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Related Author

ZHAO Tie1

YIN Tingting2

ZHANG Yingze1

LU Jin1

LI Ping1

WANG Guochun1

ZU Ning1

YAN Xiaoping1

Related Institution

Zhengzhou Central Hospital Affiliated to Zhengzhou University

Japan Friendship Hospital

Graduate School of Beijing University of Chinese Medicine

Guang 'anmen Hospital，China Academy of Chinese Medical Sciences

Henan Province Hospital of TCM（The Second Affiliated Hospital of Henan University of Chinese Medicine）

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