Effect of Combined Treatment of Weifu Formula and Chemotherapy on the Quality of Life in Advanced Gastric Carcinoma Patients with Spleen Deficiency and Toxin Accumulation Syndrome
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Effect of Combined Treatment of Weifu Formula and Chemotherapy on the Quality of Life in Advanced Gastric Carcinoma Patients with Spleen Deficiency and Toxin Accumulation Syndrome
Journal of Traditional Chinese MedicineVol. 56, Issue 2, Pages: 120-123(2015)
FAN Jiangli, LI Dongfang, JIAO Jiao, et al. Effect of Combined Treatment of Weifu Formula and Chemotherapy on the Quality of Life in Advanced Gastric Carcinoma Patients with Spleen Deficiency and Toxin Accumulation Syndrome[J]. Journal of Traditional Chinese Medicine2015, 56(2): 120-123.
FAN Jiangli, LI Dongfang, JIAO Jiao, et al. Effect of Combined Treatment of Weifu Formula and Chemotherapy on the Quality of Life in Advanced Gastric Carcinoma Patients with Spleen Deficiency and Toxin Accumulation Syndrome[J]. Journal of Traditional Chinese Medicine2015, 56(2): 120-123.DOI: 10.13288/j.11-2166/r.2015.02.009.
Effect of Combined Treatment of Weifu Formula and Chemotherapy on the Quality of Life in Advanced Gastric Carcinoma Patients with Spleen Deficiency and Toxin Accumulation Syndrome
Objective To observe the effect of combined treatment of Weifu Formula and chemotherapy on the quality of life in advanced gastric carcinoma patients with spleen deficiency and toxin accumulation syndrome.Methods In total 60 cases of advanced gastric cancer patients with spleen deficiency and toxin accumulation syndrome were randomly divide into a control group and a treatment group
with 30 cases in each. Both groups were treated with FOLFOX6 regimen
but the treatment group was added with Weifu Formula
a Chinese herbal decoction
one dose daily. 14-days was a treatment course
and both groups were observed for 2 courses. Changes in QLQ-C30 score
Piper fatigue scale( PFS) score
TCM syndrome score
Karnofsky score
as well as gastrointestinal adverse effects and myelosuppression were observed. Results After treatment
the improvement of QLQ-C30 scores
PFS scores
TCM syndrome scores
and Karnofsky scores in the treatment group were better than those in the control group( P < 0. 05). Myelosuppression and gastrointestinal toxicity were milder in the treatment group than that in the control group
with significant differences( P < 0. 05). Conclusion Weifu Formula can improve the quality of life in advanced gastric carcinoma patients with spleen deficiency and toxin accumulation syndrome. It also helpful in alleviating myelosuppression and gastrointestinal adverse effects caused by chemotherapy.
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Related Author
ZHAN Wenhao
DING Qian
DONG Zhiwei
LI Ting
FU Shumei
TIAN Ning
WANG Xianliang
ZHANG Jingyi
Related Institution
Guangdong Hospital of Integrated Traditional Chinese and Western Medicine Affiliated to Guangzhou University of Chinese Medicine
Jinan Vocational College of Nurisng,Shandong Pronvince
First Teaching Hospital of Tianjin University of Traditional Chinese Medicine/ National Clinical Research Center for Chinese Medicine
Tianjin University of Traditional Chinese Medicine