Observation on the Efficacy of Yiqi Mingmu Wan with Western Medicine in the Treatment of Anterior Ischemic Optic Neuropathy

LI Bo; LI Chuanke

doi:10.13288/j.11-2166/r.2015.03.013

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Observation on the Efficacy of Yiqi Mingmu Wan with Western Medicine in the Treatment of Anterior Ischemic Optic Neuropathy

更新时间：2021-11-17

- Observation on the Efficacy of Yiqi Mingmu Wan with Western Medicine in the Treatment of Anterior Ischemic Optic Neuropathy
- Journal of Traditional Chinese Medicine Vol. 56, Issue 3, Pages: 228-230(2015)
- 作者机构：
  
  湖南省中医药大学第一附属医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2015.03.013
  CLC： R774.6
- Published：2015
- 稿件说明：
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[1]李波,李传课.益气明目丸联合西药治疗前段缺血性视神经病变24例疗效观察[J].中医杂志,2015,56(03):228-230.

LI Bo, LI Chuanke. Observation on the Efficacy of Yiqi Mingmu Wan with Western Medicine in the Treatment of Anterior Ischemic Optic Neuropathy[J]. Journal of Traditional Chinese Medicine2015, 56(3): 228-230.
[1]李波,李传课.益气明目丸联合西药治疗前段缺血性视神经病变24例疗效观察[J].中医杂志,2015,56(03):228-230. DOI： 10.13288/j.11-2166/r.2015.03.013.

LI Bo, LI Chuanke. Observation on the Efficacy of Yiqi Mingmu Wan with Western Medicine in the Treatment of Anterior Ischemic Optic Neuropathy[J]. Journal of Traditional Chinese Medicine2015, 56(3): 228-230. DOI： 10.13288/j.11-2166/r.2015.03.013.

摘要

目的观察益气明目丸联合西药治疗脾胃气虚型前段缺血性视神经病变的临床疗效。方法收集前段缺血性视神经病变脾胃气虚型患者24例（25只眼）

口服益气明目丸

每次9 g

每日3次。同时配合维生素B120 mg、甲钴胺片500μg

每日3次。2周为1个疗程

共治疗4个疗程。检测治疗前后患者的视力、视野、眼底及眼底荧光血管造影术（FFA）变化

判定视力疗效和中医证候疗效。结果 24例患者25只眼中视力疗效总有效21只眼（84%）;中医证候疗效总有效22只眼（88%）。治疗后视力、视野平均光敏感度均较治疗前明显升高（P<0.01）。治疗后21只眼（84%）眼底改善。17例（18只眼）行FFA检查者治疗后视盘荧光充盈迟缓明显低于治疗前（P<0.05）。结论益气明目丸联合西药治疗脾胃气虚型前段缺血性视神经病变能明显改善视功能。

Abstract

Objective To observe the clinical efficacy of Yiqi Mingmu Wan（ YQMMW） combined with western medicine to treat anterior ischemic optic neuropathy of spleen and stomach qi deficiency syndrome. Methods A total of 24 anterior ischemic optic neuropathy patients（ 25 eyes） with spleen and stomach qi deficiency syndrome were included and they were given YQMMW orally

9 g each time

3 times a day

with vitamin B1 20 mg and mecobalamin tablets 500 μg

3 times a day. One course of the treatment was for 2 weeks

with a total of 4 courses. The visual acuity

visual field

fundus and the changes of fundus fluorescein angiography（ FFA） were detected before and after treatments to determine the efficacy in vision and TCM syndromes. Results Totally 21 eyes（ 84%） out of 25 eyes were effective in vision and 22 eyes（ 88%） were effective in TCM syndromes. After treatments

the visual acuity and mean light sensitivity of visual field were significantly improved（ P < 0. 01）

and 21 eyes（ 84%） showed fundus improvements. Also

17 patients（ 18 eyes） undergone FFA revealed faster fluorescence filling after treatments（ P < 0. 05）. Conclusion YQMMW combined with western medicine can significantly improve the visual function of anterior ischemic optic neuropathy patients with spleen and stomach qi deficiency syndrome.

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