LIU Chunyan, SHEN Lin, ZHANG Shuai, et al. Treatment of 30 Cases of Premature Ventricular Beats with Fulvning Granule: a Randomize-Controlled Double-Blind Clinical Trial[J]. Journal of Traditional Chinese Medicine2015, 56(7): 583-585.
LIU Chunyan, SHEN Lin, ZHANG Shuai, et al. Treatment of 30 Cases of Premature Ventricular Beats with Fulvning Granule: a Randomize-Controlled Double-Blind Clinical Trial[J]. Journal of Traditional Chinese Medicine2015, 56(7): 583-585.DOI: 10.13288/j.11-2166/r.2015.07.012.
Treatment of 30 Cases of Premature Ventricular Beats with Fulvning Granule: a Randomize-Controlled Double-Blind Clinical Trial
Objective To observe the clinical efficacy and safety of Fulvning Granule on premature ventricular beats. Methods Totally 60 patients were randomized into treatment group and control group
each of 30 cases.The treatment group was treated by Fulvning Granule 10 g each time
twice a day
and Propafenone placebo 150 mg each time
three times a day; the control group was given Fulvning Granule placebo 10 g each time
twice a day
and Propafenone 15 g each time
three times a day with a course of 4 weeks. The therapeutic effect on premature beat and Chinese medicine syndrome and the safety were observed. Result The total effective rate of premature beats in both treatment group and control group was 36. 67%
showing no statistical significance( P > 0. 05). The total effective rate of Chinese medicine sydnrome of the treatment group was 86. 67%
and that of the control group was53. 33%
the efficacy of the treatment group superior to that of the control group( P < 0. 05). There was no adverse reactions during the research. Conclusion Fulvning Granule has therapeutic equivalence to Propafenone on treating premature ventricular beats.
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