Objective To evaluate the clinical effect of Xihuang Wan combined with chemotherapy treating cancer using Meta-analysis. Methods Review all published literature from Journal Full-Text Database of China National Knowledge Infrastructure

VIP Data

Wanfang Data

Cochrane library

Pub Med and EMbase up to September of 2014. Include study papers of randomized controlled trials of Xihuang Wan combined with chemotherapy and chemotherapy alone in treating cancer. Adopt same data extraction forms to record patients’ general information

intervention and observation indexes. Use bias risk evaluation tool offered by Cochrane collaboration to do methodological quality assessment on included studies. Make meta-analysis of patients’ short-term effective rate and improvement rate of Karnofsky performance status（ KPS） scores with software Revman 5. 3. Results Nine studies were included totally

516 patients involved. Included papers were all in Chinese. Level of literature quality was a little low. Meta analysis results showed that compared with chemotherapy alone

patients’ short-term effective rate [OR = 1. 49

95%CI（1. 03

2. 15）

Z = 2. 13

P = 0. 03

9 papers] and improvement rate of KPS scores [OR = 2. 71

95% CI（1. 47

4. 97）

Z = 3. 21

P = 0. 001

5 papers]were increased by treatment of Xihuang Wan combined with chemotherapy. Conclusion Compared with chemotherapy alone

Xihuang Wan combined with chemotherapy may increase short-term effective rate of cancer and be effective in improving KPS scores.