Adjuvant Therapy with Fulvning Granule（ 复律宁颗粒） in Treating 30 Cases of Chronic Heart Failure with Arrhythmia with Qi and Yin Deficiency Syndrome: a Clinical Observation

TANG Nuo; CHEN Cheng; QU Chang; HE Yan; WANG Youhua; DENG Bing; Tang Jingyi

doi:10.13288/j.11-2166/r.2015.18.010

您当前的位置：

首页 >

文章列表页 >

Adjuvant Therapy with Fulvning Granule（复律宁颗粒） in Treating 30 Cases of Chronic Heart Failure with Arrhythmia with Qi and Yin Deficiency Syndrome: a Clinical Observation

更新时间：2021-11-17

- Adjuvant Therapy with Fulvning Granule（复律宁颗粒） in Treating 30 Cases of Chronic Heart Failure with Arrhythmia with Qi and Yin Deficiency Syndrome: a Clinical Observation
- Journal of Traditional Chinese Medicine Vol. 56, Issue 18, Pages: 1564-1568(2015)
- 作者机构：
  
  1. 上海中医药大学附属龙华医院
  2. 苏州市中医医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2015.18.010
  CLC： R541
- Published：2015
- 稿件说明：
移动端阅览
[1]汤诺,陈成,曲畅,何燕,王佑华,邓兵,唐靖一.复律宁颗粒辅助治疗气阴两亏型慢性心力衰竭合并心律失常30例临床观察[J].中医杂志,2015,56(18):1564-1568.

TANG Nuo, CHEN Cheng, QU Chang, et al. Adjuvant Therapy with Fulvning Granule（复律宁颗粒） in Treating 30 Cases of Chronic Heart Failure with Arrhythmia with Qi and Yin Deficiency Syndrome: a Clinical Observation[J]. Journal of Traditional Chinese Medicine2015, 56(18): 1564-1568.
[1]汤诺,陈成,曲畅,何燕,王佑华,邓兵,唐靖一.复律宁颗粒辅助治疗气阴两亏型慢性心力衰竭合并心律失常30例临床观察[J].中医杂志,2015,56(18):1564-1568. DOI： 10.13288/j.11-2166/r.2015.18.010.

TANG Nuo, CHEN Cheng, QU Chang, et al. Adjuvant Therapy with Fulvning Granule（复律宁颗粒） in Treating 30 Cases of Chronic Heart Failure with Arrhythmia with Qi and Yin Deficiency Syndrome: a Clinical Observation[J]. Journal of Traditional Chinese Medicine2015, 56(18): 1564-1568. DOI： 10.13288/j.11-2166/r.2015.18.010.

摘要

目的评价复律宁颗粒辅助治疗气阴两亏型慢性心力衰竭合并心律失常的临床疗效和安全性。方法60例中医辨证为气阴两亏型的慢性心力衰竭合并心律失常患者随机分为治疗组和对照组各30例。对照组给予西医规范化治疗

治疗组在对照组治疗基础上加用复律宁颗粒

每次15 g

每日2次。两组疗程均为4周。观察两组患者NYHA心功能分级、六分钟步行距离、心脏彩色超声、动态心电图、明尼苏达心衰生活质量（LHFQ）评分（包括体力、情绪、社会、经济）、中医证候评分及安全性

治疗后评价心功能疗效和心律失常疗效。结果治疗后两组心功能疗效（治疗组总有效率76.67%

对照组为50.00%）及心律失常疗效（治疗组总有效率66.67%

对照组为30.00%）比较差异均有统计学意义（P<0.05或P<0.01）

治疗组优于对照组。治疗后两组中医证候积分

LHFQ体力、经济、社会评分及总积分均较治疗前降低

而六分钟步行距离提高（P<0.01）;并且治疗后治疗组中医证候积分

LHFQ体力、经济、社会评分及总积分低于对照组

六分钟步行距离高于对照组（P<0.05）。两组治疗前后心脏彩超各指标比较差异均无统计学意义（P>0.05）。结论复律宁颗粒辅助治疗气阴两亏型慢性心力衰竭患者可改善心功能和生活质量

安全有效。

Abstract

Objective To evaluate clinical curative effect and safety of Fulvning Granule as an adjuvant therapy in treating 30 cases of chronic heart failure with arrhythmia with Qi and Yin deficiency. Methods Sixty cases of chronic heart failure with arrhythmia with qi and yin deficiency according to Chinese Medicine syndrome differentiation were randomly divided into a treatment group and a control group

with 30 cases in each. Control group was given Western medicine standardized treatment

while treatment group used Fulvning Granule additionally on the base of the treatment of control group

15 g each time

twice a day. Courses of the treatment of two groups were both 4 weeks.The New York Heart Association（ NYHA） cardiac functional grading

Six-Minute Walk Distance

cardiac color ultrasound

dynamic electrocardiogram

Minnesota Living with Heart Failure Questionnaire（ LHFQ） scores（ including physical

emotional

economic

and social items）

traditional Chinese medicine（ TCM） syndrome scores

and treatment safety of patients in two groups were observed. Then

the curative effect on cardiac function and arrhythmia was evaluated. Results Curative effects on cardiac function（ the total effective rates was 76. 67% in treatment group

and 50. 00% in control group） and arrhythmia（ the total effective rates was 66. 67% in treatment group

and30. 00% in control group） in two groups after treatment were significantly different（ P < 0. 05 or P < 0. 01）. Treatment group was superior to control group. After treatment

TCM syndrome scores

LHFQ physical

economic

and social scores

as well as the total LHFQ scores decreased

while Six-Minute Walk Distance increased in both groups（ P < 0. 01）

especially in the treatment group（ P < 0. 05）. There was no statistically significant difference in all indexes of cardiac color ultrasound between two groups before and after treatment（ P > 0. 05）. Conclusion As an adjuvant therapy for chronic heart failure with Qi and Yin deficiency

Fulvning Granule can improve cardiac function and quality of life effectively and safely.

关键词

Keywords

references

查看原文

Views

206

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effect of Optimized New Shengmai Powder （优化新生脉散方） on Exercise Tolerance in Patients with Chronic Heart Failure of Qi Deficiency，Blood Stasis and Fluid Retention Syndrome：A Randomized，Double-Blind，Placebo-Controlled Trial

Clinical Observation on 310 Cases of Chronic Heart Failure with Qi Deficiency and Blood Stasis Syndrome Treated by Shenkui Tongmai Granules （参葵通脉颗粒）

Clinical Observation on Fulyuning Keli（复律宁颗粒） Combined with Western Medicine in Treating 40 Cases of Chronic Heart Failure Complicated with Arrhythmia of Both Qi and Yin Deficiency Type

Effect of Yang-Reinforcing and Blood-Activating Therapy on the Long-Term Prognosis for Dilated Cardio-myopathy Patients with Yang Deficiency and Blood Stasis Syndrome：A Retrospective Cohort Study

The Effect of Yiqi Huoxue Formula （益气活血方） in the Treatment of Chronic Pulmonary Heart Disease and Heart Failure with Qi Deficiency and Blood Stasis Pattern of 58 Cases： A Randomized Controlled Trial

Related Author

WANG Xianliang

ZHANG Jingyi

GE Zhao

LIU Tongzuo

ZHANG Maozhe

WANG Shuai

ZHAO Zhiqiang

BI Yingfei

Related Institution

First Teaching Hospital of Tianjin University of Traditional Chinese Medicine/ National Clinical Research Center for Chinese Medicine

Tianjin University of Traditional Chinese Medicine

Jiangsu Province Hospital of Chinese Medicine

Yangzhou Hospital of Chinese Medicine

Jiangsu Province Hospital on Integration of Chinese and Western Medicine

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰