Objective To investigate the changes of TCM Syndrome Types in patients with liver cancer before and after interventional embolization

chemotherapy and to provide ideas for clinical treatment. Methods A retrospective study was performed in 312 patients with primary liver cancer who underwent interventional embolization chemotherapy

the"Retrospective chart review of patients with liver cancer before and after intervention"were used to collect the patients’ TCM diagnostic data

including 55 variables

such as symptoms

signs

tongue pulse and so on

Analysis of sample frequency statistics for all symptoms

signs

tongue and pulse and other diagnostic information were taken

if the occurrence rate of the variables of the syndrome indicators is less than 2%

they would be deleted

the remaining variables are analysed by hierarchical variable clustering analysis to determine the syndrome elements of each class

to sum up each type of TCM syndrome type

and to compare the characteristics of TCM syndrome types before and after intervention. Results Before and after interventional therapy of primary liver cancer

the TCM syndromes were mainly Liver Qi stagnation syndrome

blood stasis syndrome

damp heat syndrome

spleen deficiency syndrome and yin deficiency syndrome. The difference in the overall distribution of basic syndromes before and after intervention was statistically significant（ P < 0. 01）; After the intervention

Liver Qi stagnation syndrome and damp heat syndrome were significantly increased

spleen deficiency syndrome and yin deficiency syndrome were significantly reduced（ P < 0. 05）. Conclusion TCM Pathogenesis of Liver cancer after interventional embolization chemotherapy tends to be Liver Qi stagnation syndrome and damp heat syndrome

in clinical work attention should be paid to the clinical treatment strategy of soothing-liver cholaneresis and eliminating dampness and heat.