From the theory of Qi（ energy）-Jing（ essence）-Shen（ spirit）

combination of shape and soul theory

and the theory of five Shenzang（ viscera with spirit）

this article illustrates that the cognitional function is based on the essence of Zang-fu. Then

from the views of Yang-qi promoting Shen

and the Du meridian being the sea of Yang-meridians

the article discuss the idea that Du meridian is the hub of Zang-fu physiological function and cognition by regulation Yang-qi of the body. Based on these

the article further raise that

construction of cognitional function theoretical system in Chinese medicine should be based on the initial thinking of "Zang-fu functioning as the basis of cognitional function

while Du meridian functioning as the hub".