Clinical Observation on Jiannao Yifang（健脑1方） Combined with Western Medicine in Treating 30 Cases of Vascular Dementia

CHEN Ting; WU Wei

doi:10.13288/j.11-2166/r.2016.04.010

您当前的位置：

首页 >

文章列表页 >

Clinical Observation on Jiannao Yifang（健脑1方） Combined with Western Medicine in Treating 30 Cases of Vascular Dementia

更新时间：2021-11-17

- Clinical Observation on Jiannao Yifang（健脑1方） Combined with Western Medicine in Treating 30 Cases of Vascular Dementia
- Journal of Traditional Chinese Medicine Vol. 57, Issue 4, Pages: 307-310(2016)
- 作者机构：
  
  广州中医药大学第一附属医院
- 作者简介：
- 基金信息：
- DOI：10.13288/j.11-2166/r.2016.04.010
  CLC： R749.13
- Published：2016
- 稿件说明：
移动端阅览
[1]陈婷,吴伟.健脑1方联合西药治疗血管性痴呆30例临床观察[J].中医杂志,2016,57(04):307-310.

CHEN Ting, WU Wei. Clinical Observation on Jiannao Yifang（健脑1方） Combined with Western Medicine in Treating 30 Cases of Vascular Dementia[J]. Journal of Traditional Chinese Medicine2016, 57(4): 307-310.
[1]陈婷,吴伟.健脑1方联合西药治疗血管性痴呆30例临床观察[J].中医杂志,2016,57(04):307-310. DOI： 10.13288/j.11-2166/r.2016.04.010.

CHEN Ting, WU Wei. Clinical Observation on Jiannao Yifang（健脑1方） Combined with Western Medicine in Treating 30 Cases of Vascular Dementia[J]. Journal of Traditional Chinese Medicine2016, 57(4): 307-310. DOI： 10.13288/j.11-2166/r.2016.04.010.

摘要

目的观察健脑1方治疗血管性痴呆的临床疗效及安全性。方法收集血管性痴呆气虚痰瘀证患者60例

随机分为治疗组和对照组各30例。两组均给予基础治疗的同时

治疗组联合健脑1方治疗

每日1剂

对照组予尼莫地平片

每次20 mg

每日3次

两组疗程均为6周。治疗前后记录两组患者的简易精神状态检查量表（MMSE）评分、日常生活自理能力量表（ADL）评分、神经精神科问卷（NPI）评分、中医证候积分的变化

评价认知功能、行为能力、精神行为及中医证候疗效

记录治疗过程中的不良反应。结果认知功能临床疗效比较:治疗组总有效率80.00%

对照组53.33%

治疗组优于对照组（P<0.05）;行为能力临床疗效比较:治疗组总有效率23.33%

对照组为30.00%

两组比较差异无统计学意义（P>0.05）;精神行为临床疗效比较:治疗组总有效率6.67%

对照组为6.67%

两组比较差异无统计学意义（P>0.05）;中医证候疗效比较:治疗组总有效率56.67%

对照组为10.00%

治疗组优于对照组（P<0.01）。两组患者治疗后MMSE评分均较本组治疗前提高

而ADL评分均降低（P<0.01）。治疗组治疗后中医证候积分较治疗前降低（P<0.01）。两组治疗后中医证候积分组间比较差异有统计学意义（P<0.01）。结论健脑1方治疗血管性痴呆可提高患者认知功能、日常生活能力

改善患者的中医临床症状

不良反应少。

Abstract

Objective To observe clinical curative effects and safety of Jiannao Yifang in the treatment of vascular dementia. Methods Sixty patients with vascular dementia with Qi deficiency to phlegm and stasis were collected and randomly divided into the treatment group and the control group

with 30 cases in each group. Two groups were given basic treatment（ nimodipine

20 mg each time

3 times a day）

and the treatment group also took Jiannao Yifang

1 dose a day. Both groups were treated for 6 weeks. Before and after treatment

score of mini-mental state examination scale（ MMSE）

score of ability of daily living scale（ ADL）

score of neuropsychiatric questionnaire（ NPI）

and the change of Chinese medical syndrome integral of patients in the two groups were recorded. The cognitive function

disposing capacity

spiritual behavior

and curative effects of Chinese medical syndrome were also evaluated. Results In clinical curative effects of cognitive function

effective cases accounted for 80. 00% of all cases in the treatment group

and 53. 33% in the control group. The treatment group was better than the control group（ P < 0. 05）. In clinical curative effects of disposing capacity

effective cases accounted for 23. 33% of all cases in the treatment group

and 30. 00% in the control group. There was no significant difference between the two groups（ P > 0. 05）. In clinical curative effects of spiritual behavior

effective cases accounted for 6. 67% of all cases in the treatment group

and 6. 67% in the control group. There was no significant difference between the two groups（ P >0. 05）. In curative effects of Chinese medical syndrome

effective cases accounted for 56. 67% of all cases in the treatment group

and 10. 00% in the control group. The treatment group was better than the control group（ P <0. 01）. MMSE scores of both groups after treatment were higher

but ADL scores decreased than those before treatment（ P < 0. 01）. Chinese medical syndrome integral of the treatment group after treatment was lower than that before treatment（ P < 0. 01）. There was statistically significant difference in Chinese medical syndrome integral between two groups after treatment（ P < 0. 01）. Conclusion The treatment of vascular dementia with Jiannao Yifang may improve cognitive function

ability of daily living and clinical symptoms of Chinese medicine of patients

with less adverse reaction.

关键词

Keywords

references

查看原文

Views

205

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Clinical Observation on Comprehensive Treatment of Basic Western Medicine and Traditional Chinese Medicine in Treating 110 Cases of Vascular Dementia

Clinical Observation on 103 Cases of Vascular Dementia Adopting Combined Treatment of Integrated Traditional Chinese Medicine Therapy with Western Medicine

Effects of Tongluo Fuzheng Decoction （通络扶正汤） as an Adjunctive Therapy on Coagulation and Vascular Endothelial Function in Patients with Ischemic Stroke of the Acute Stage with Wind-Phlegm and Blood Stasis Syndrome

Differentiation and Treatment of Vascular Dementia Applying the Method of Promoting Yang

The Effect of Modified Ditan Decoction （涤痰汤） on Cognitive Function and Resting-State Functional Magnetic Resonance Imaging of the Brain in Chronic Intermittent Hypoxia Model Rats

Related Author

HU Yueqiang

TANG Nong

WU Lin

LING Jianghong

TAN Kaiwen

LIANG Ni

LU Changjun

HU Yueqiang

Related Institution

Liuzhou Traditional Chinese Medical Hospital

Nanning Traditional Chinese Medicine Hospital

The First Affiliated Hospital of Guangxi Medical University

Guangxi University of Chinese Medicine

The First Affiliated Hospital of Guangxi University of Chinese Medicine

Address：No.16, Nanxiao street, Dongzhimen, Dongcheng District, Beijing Postal code：100700
Tel：010-64035632 Email：jtcmcn@188.com
Technical support is provided by Beijing Founder electronics co., LTD 京ICP备09064830号-19 京公网安备11010102007558号
It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.

⁰