This paper is to explore the correlation between "toxicity"pathogen causing disease and chronic heart failure（ CHF） onset. "Toxicity"pathogen causing disease has the characteristics of rapid happening

quick transmission

complicated

changeable

difficult to treat

lingering illness

destroying body form

injuring Zang-fu viscera structure and function

causing serious harm to human body

etc. CHF onset has the characteristics of multiple pathogen combination

obstinate

complicated condition

involving many organs

changeful

threat to life

etc. The similarity of onset characteristics showed that there might be toxicity pathogen in the process of CHF onset. Medicine of removing toxicity should be used in treatment. Syndrome differentiation according to the toxicity pathogen formation mechanism and different attachment of pathogen should be conducted in clinical treatment. It is revealed from studies that Chinese medicine treatment has effects of improving hemodynamic parameters in animal with cardiac insufficiency

inhibiting apoptosis of myocardial cells

preventing myocardial hypertrophy

inhibiting the expression of oxidase and excessive activation of renin angiotensin system

etc. Moreover

Chinese medicine treatment might improve quality of life and heart function of CHF patients.