SAPHO（ synovitis

acne

pusfulosis

hyperositosis

osteitis） Syndrome is a rare chronic aseptic inflammation which can involve the skin and joints. YAN Xiaoping holds that the root cause of etiology and pathogenesis of SAPHO Syndrome is deficiency of liver and kidney. Wind

cold

dampness and other pathogens invade and blockade muscles

tendons

bones

joints and channel-collaterals. Thus

Qi and blood run sluggishly. Clinical manifestation is muscles and joints pain. Internal retention of cold-damp transforms heat from excessive Yang. Heat-toxicity generates from inside. Corruption pyogenesis manifests metacarpophalangeal impetigo and severe acne. As for treatment

YAN Xiaoping thinks highly of reinforcing the kidney

strengthening the healthy energy

nourishing the liver and tendons to even reinforcing the liver and kidney. Dispelling wind

eliminating dampness

removing obstruction in collaterals and relieving joints are strengthened to activate joints. YAN Xiaoping emphasizes cooling blood

removing toxicity

clearing heat and eliminating dampness to eliminate internal retention of cold-damp pathogens. YAN Xiaoping also lays stress on invigorating spleen

eliminating dampness and diffusing lung-defense phase

which means regulating spleen and lung.