Based on Prof. ZHOU Zhongying’s understanding of epidemic hemorrhagic fever（ pestilent and macula heat）

the authors summarize that the academic characteristics of exogenous febrile disease mainly include 5 aspects below: emphasize pathological factors; pay attention to the evolution of disease; advocate theory composition and academic innovation; explore specific treatment; multi uses of one method and adopt multi methods clinically. From the understanding of pestilent and macula heat

the authors think that Prof. ZHOU inherits traditional understanding and makes innovation to theory. Prof. ZHOU gets comprehensive mastery and has key cognition. He keeps mastering Chinese medicine theory strictly and treats some specific diseases flexibly. The analysis of his academic characteristics of treating pestilent and macula heat might provide useful reference for improving research levels of Chinese medicine exogenous febrile disease.