Objective To explore the relationship between Gouqizi [Fructus Lycii

枸杞子] and "getting inflamed"

as well as the possible influencing factors. Methods The questionnaire about "Gouqizi and getting inflamed"was designed. The ways of We Chat platform and community survey were both used. The situation of Gouqizi taking

the condition of getting inflamed and the symptoms manifestation of the respondents were retrospectively investigated and analyzed. The relationship between dose

time

ways of Gouqizi taking

and combination with other herbs and "getting inflamed"was analyzed. Results Totally

617 respondents were included

with 228 cases took Gouqizi alone（ 36. 95%） and 389 cases those had Gouqizi combined with other herbs（ 63. 05%）. The most common way to take Gouqizi was drinking tea made of Gouqizi（ 77. 96%）

having soup with Gouqizi（ 48. 30%）

and direct chewing Gouqizi（ 35. 98%）. The most common herbs in combination with Gouqizi were Juhua [Flos Chrysanthemi

菊花]（ 68. 38%）

Jinyinhua [Flos Lonicerae

金银花]（ 23. 91%） and Maidong [Radix Ophiopogonis

麦冬]（ 21. 85%）. Among 617 respondents

161 respondents（ 26. 09%） got "inflamed"after taking Gouqizi. The manifestations of "getting inflamed " were always dry mouth and throat（ 74 cases

11. 99%）

epistaxis（ 70 cases

11. 35%）

as well as inflamed and sore throat（ 46 cases

7. 46%）. Dose

ways（ chewing）

as well as combining herbs had close relationship with "getting inflamed". After taking Gouqizi combined with Juhua

Jinyinhua

Maidong and Chenpi [Pericarpium Citri Reticulatae

陈皮]

the proportion of occuring "getting inflamed"decreased significantly（ P < 0. 05）. Conclusion After taking Gouqizi

some people may have "inflamed"symptoms. With reasonable dose and taking ways

and combined with some other herbs might reduce the occurrence of "getting inflamed".